diet and lifestyle program for Obesity

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Michigan, Ann Arbor, MI
Obesity
diet and lifestyle program - Behavioral
Eligibility
18 - 65
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a very low carbohydrate diet can be used to treat young adults with type 2 diabetes.

See full description

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether diet and lifestyle program will improve 1 primary outcome and 1 secondary outcome in patients with Obesity. Measurement will happen over the course of 4 months.

4 months
Change in HbA1c
Change in percent bodyweight

Trial Safety

Safety Estimate

1 of 3

Trial Design

1 Treatment Group

diet and lifestyle program
1 of 1
Experimental Treatment

This trial requires 30 total participants across 1 different treatment group

This trial involves a single treatment. Diet And Lifestyle Program is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 1 & 2 and have already been tested with other people.

diet and lifestyle program
Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
diet and lifestyle program
2017
Completed Phase 2
~150

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 4 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 4 months for reporting.

Who is running the study

Principal Investigator
L. S.
Prof. Laura Saslow, Assistant Professor
University of Michigan

Closest Location

University of Michigan - Ann Arbor, MI

Eligibility Criteria

This trial is for patients born any sex between 18 and 65 years old. There are 6 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Age 18-25
Obese (BMI ≥ 30)
Sufficient control over diet
Access to internet and texting
Living in the United States
Willing and able to follow intervention and complete measurements

Patient Q&A Section

What are the signs of obesity?

"There are a number of signs and symptoms that can result in the suspicion of a child having central obesity. However, the diagnosis may only be supported by a physical examination, an ultrasound, or a computed tomography (CT) scan. A referral to a pediatric endocrinologist or pediatric neurologist can be a useful adjunct in the management of obesity." - Anonymous Online Contributor

Unverified Answer

What are common treatments for obesity?

"Obesity is commonly treated using diet therapy, exercise, cognitive behavioural therapy (CBT), weight loss surgery, and medication.\n\nIn 2018 the UK registered a total of 1,028,000 deaths from cancer. Lung cancer was the main cause of death. On average, 3.4 people per 1,000 in the UK died from cancer, while 1.9% of cancers occurred in men and a further 4.5% occurred in women." - Anonymous Online Contributor

Unverified Answer

Can obesity be cured?

"Obesity is one of the most common physical problems seen in modern medicine with the incidence increasing steadily. The rate of childhood obesity is very high with a number of other medical problems related to obesity being observed. There are many treatments available for the treatment of weight problems, the evidence of which is not good. It is still difficult to prove that one treatment is better than another. Although there are many different treatments for obesity they have not yet reached a situation where they may be used for everyone. In the long term it is likely that the obese will seek to decrease their weight but many have not succeeded in this aim. If the underlying causes of the obesity remain untreated at this time, people will continue to become more and more overweight." - Anonymous Online Contributor

Unverified Answer

How many people get obesity a year in the United States?

"The number of people who are obese in the USA has been increasing with a rate of about 1.5% per year. Obesity in the United States is now the most prevalent chronic health problem in Americans." - Anonymous Online Contributor

Unverified Answer

What causes obesity?

"Over the years, many authors have made the point that, although the genesis of obesity is shrouded in mystery, it is certainly not due to genetic factors alone. Obesity in fact has multiple causes; its link to certain inherited diseases is just one of them. Clearly, the environment plays a significant role. And while the environment does not explain all obesity, it definitely influences the genesis of the disease through dietary changes. Obesity is a complex and multidimensional condition, with many risks related to obesity that are still being researched. Although obesity is a multifactorial condition, this definition means that the underlying causes of this disease can be split into genes, genetics, and environment." - Anonymous Online Contributor

Unverified Answer

What is obesity?

"Obesity is defined as being more than 20% over your ideal body weight. Body mass index (BMI or BMI) is not a good measurement tool for obesity. In many cases, individuals who may be obese by BMI may have a normal waist circumference (WC).\n" - Anonymous Online Contributor

Unverified Answer

Is diet and lifestyle program typically used in combination with any other treatments?

"A diet and lifestyle program consisting of weight loss, exercise training and counseling may help diminish obesity for some individuals. However, this information is based upon the results of a previously completed trial. Results from a recent paper must be viewed with caution when extrapolating to the entire patient population. Because of the absence of other potential treatment for obese patients in the literature, a randomized controlled trial of an intensive behavioral program, similar to the one described here, would need to be performed before any definite conclusions can be reached." - Anonymous Online Contributor

Unverified Answer

What does diet and lifestyle program usually treat?

"In this large study of the use of diet and lifestyle to treat obese children, we have shown that the majority of children fail to make statistically and clinically significant weight loss. Findings from a recent study of this study suggest that it is difficult to change the current state of obesity in children and adolescents because they are not eager or competent enough to change their diets and lifestyles in the absence of a compelling educational effort. Findings from a recent study should emphasize the need for a complete rehabilitation of children and adolescents by nutrition educators and practitioners." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of obesity?

"Despite a large literature search, there remain inconsistencies in our understanding about the cause of obesity. Findings from a recent study in this study indicate that obesity is a condition that is more complex than simply, the ultimate consequence of a shortage of energy. Many factors in our culture may contribute to obesity, but unfortunately we are all too often distracted by the fast pace of the industrialized world and this will continue to be a major challenge for the next 50 years. Obesity is a disease that affects health and wellbeing of both the health care providers and the public. Preventing obesity is a challenge for us as a society." - Anonymous Online Contributor

Unverified Answer

How does diet and lifestyle program work?

"The lifestyle program results in a rapid and sustained weight loss of 6.7%. Follow-up results are available over 6 months, with no more benefit observed. The dietary program demonstrates an association between diet changes and rapid weight loss. In addition to weight loss, the patient satisfaction and health awareness are improved postoperatively." - Anonymous Online Contributor

Unverified Answer

What are the common side effects of diet and lifestyle program?

"Participants with good adherence to the diet and lifestyle regimen reported the highest satisfaction with the program, which reflects the positive effects of the intervention. In general, side effects of the program were few, and they did not have a direct negative impact on the participants." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in diet and lifestyle program for therapeutic use?

"Therapeutic diets and lifestyle programs that help fat patients regain weight by restricting or even removing food from the diets of overweight and obese individuals, can decrease body fatness significantly over periods of 2 years, but the success rate of lifestyle changes is variable. The impact of these interventions on the metabolic health of these patients, their long-term prognoses and outcomes of treatment are unknown." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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