CLINICAL TRIAL

Multimodal Teleprehabilitation for Thoracic Cancers

Recruiting · 18+ · All Sexes · Montréal, Canada

This study is evaluating whether a home-based prehabilitation program can improve outcomes for cancer patients.

See full description

About the trial for Thoracic Cancers

Eligible Conditions
Thoracic Cancers · Abdominal Cancer

Treatment Groups

This trial involves 2 different treatments. Multimodal Teleprehabilitation is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Multimodal Teleprehabilitation
BEHAVIORAL
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.

Eligibility

This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Adults who need surgery for cancer, but their surgery has been delayed because of COVID-19, are being referred by a surgeon. show original
Covered by the RAMQ
Please make sure that you have medical clearance to exercise, as advised by your physician. show original
Can understand English or French. show original
View All

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: Through study completion, for an expected duration of of 1.5 year.
Screening: ~3 weeks
Treatment: Varies
Reporting: Through study completion, for an expected duration of of 1.5 year.
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: Through study completion, for an expected duration of of 1.5 year..
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Multimodal Teleprehabilitation will improve 8 primary outcomes and 19 secondary outcomes in patients with Thoracic Cancers. Measurement will happen over the course of During baseline assessment (beginning of prehabilitation period; T0).

Serum Albumin
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0)
Assessed the degree of inflammation (<35g/L indicates high inflammation)
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0)
CRP
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0)
Assessed the degree of inflammation (>10mg/L indicates high inflammation )
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0)
Quality of Life (EQ5D)
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0), AT THE PREOPERATIVE ASSESSMENT (WITHIN THE 24 HOURS PRIOR TO SURGERY; T1) AND FURTHER AT THE 4- (T2) AND 8-WEEKS (T3) FOLLOW-UPS AFTER SURGERY
Assessed the quality of life of the previous week, on a scale of 0 to 100 ( 100 being the best health).
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0), AT THE PREOPERATIVE ASSESSMENT (WITHIN THE 24 HOURS PRIOR TO SURGERY; T1) AND FURTHER AT THE 4- (T2) AND 8-WEEKS (T3) FOLLOW-UPS AFTER SURGERY
Body Mass Index (BMI)
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0), AT THE PREOPERATIVE ASSESSMENT (WITHIN THE 24 HOURS PRIOR TO SURGERY; T1) AND FURTHER AT THE 4- (T2) AND 8-WEEKS (T3) FOLLOW-UPS AFTER SURGERY
Assessed the body composition, ranging 18 to 30 (>30 is obesity, and <18 is malnourished).
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0), AT THE PREOPERATIVE ASSESSMENT (WITHIN THE 24 HOURS PRIOR TO SURGERY; T1) AND FURTHER AT THE 4- (T2) AND 8-WEEKS (T3) FOLLOW-UPS AFTER SURGERY
Distress Thermometer
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0), AT THE PREOPERATIVE ASSESSMENT (WITHIN THE 24 HOURS PRIOR TO SURGERY; T1) AND FURTHER AT THE 4- (T2) AND 8-WEEKS (T3) FOLLOW-UPS AFTER SURGERY
Assessment of the level of anxiety and distress, on a scale from 0 to 10 (10 being the worst score).
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0), AT THE PREOPERATIVE ASSESSMENT (WITHIN THE 24 HOURS PRIOR TO SURGERY; T1) AND FURTHER AT THE 4- (T2) AND 8-WEEKS (T3) FOLLOW-UPS AFTER SURGERY
The Hospital Anxiety and Depression Scale (HADS)
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0), AT THE PREOPERATIVE ASSESSMENT (WITHIN THE 24 HOURS PRIOR TO SURGERY; T1) AND FURTHER AT THE 4- (T2) AND 8-WEEKS (T3) FOLLOW-UPS AFTER SURGERY
Assessed the degree of anxiety and depression, separately, ranging from 0 to 18 respectively (18 being the worst score).
DURING BASELINE ASSESSMENT (BEGINNING OF PREHABILITATION PERIOD; T0), AT THE PREOPERATIVE ASSESSMENT (WITHIN THE 24 HOURS PRIOR TO SURGERY; T1) AND FURTHER AT THE 4- (T2) AND 8-WEEKS (T3) FOLLOW-UPS AFTER SURGERY
See More

Who is running the study

Principal Investigator
F. C.
Prof. Franco Carli, Principal Investigator and Professor of Anesthesia
McGill University Health Centre/Research Institute of the McGill University Health Centre

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many people get abdominal cancer a year in the United States?

Based on the data from two population-based registries, in the United States, around 12.8 million people get cancer of the abdomen a year. The most common types of cancer of the abdomen are squamous cell carcinoma and colorectal cancer.

Anonymous Patient Answer

What is abdominal cancer?

Abdominal cancer is a form of cancer that develops mostly in the lining of organs and other internal organs. This disorder is the ninth most common form of cancer in the body. While it is difficult to differentiate a colon cancer in an abdominal area from an actual colon cancer, the presence of bleeding stool or swelling that can be detected through inspection are indicative of abdominal cancer. Other symptoms can include blood in the stool, vomiting, constipation, and diarrhea.

Anonymous Patient Answer

Can abdominal cancer be cured?

Even when abdominal cancers are cured, the possibility that others may be cured with the same method remains. While a cure cannot be achieved, and treatment does not address the cause, surgery may reduce the burden of disease in some patients but not relieve symptoms.

Anonymous Patient Answer

What causes abdominal cancer?

The two main causes of cancer in children are related both to genetic and environmental factors. In general, if the parents are living, the children are also living in the same environment and are also exposed to many of the same risk factors. Smoking is the strongest environmental risk factor, followed by alcohol consumption (drinking alcohol is known to be associated with stomach cancer). A lack of exposure to asbestos is the most frequently cited reason for stomach cancer in children. If the exposures come from early childhood, the risk of stomach cancer increases. Some environmental factors are more important than others in terms of the actual risk of cancer. For example, the risk of cancer increases dramatically if a parent has stomach cancer.

Anonymous Patient Answer

What are the signs of abdominal cancer?

Symptoms in patients with locally symptomatic hepatocellular carcinoma are similar to those of the general population. Asymptomatic HCC presents mostly with fatty liver on ultrasound. Although a significant proportion of patients with abdominal cancer do not have symptoms, the symptoms reported are often vague. The clinician should be alert to these symptoms in order to suspect an underlying cancer.

Anonymous Patient Answer

What are common treatments for abdominal cancer?

Very common cancers treated with surgery or radiotherapy include gastric cancer, colon cancer, lung cancer, rectal cancer, larynx cancer, ovarian cancer, cervical cancer, oral cancer, brain cancer (glioma, glioblastoma and metastatic cancers), kidney cancer and many others.

Anonymous Patient Answer

Who should consider clinical trials for abdominal cancer?

The vast majority of oncoethicists would consider clinical trials for ACC. The need for clinical trials depends upon the clinical characteristics of the condition, the type of chemotherapy regimen, the patient's age, and disease stage.

Anonymous Patient Answer

Does abdominal cancer run in families?

This is the first time that a high proportion of children with an ACC was found to have an associated family history of cancer. Data from a recent study suggest common genetic predisposition to both primary and advanced cancers (particularly early stage cancers).

Anonymous Patient Answer

What are the latest developments in multimodal teleprehabilitation for therapeutic use?

Teleprehabilitation is feasible in a multidisciplinary clinic setting. A significant proportion of the patients had been discharged after the treatment was discharged by means of the multidisciplinary telemedicine team. For the first time, we have been able to use the telerehabilitation approach in a routine context as a first line of treatment in this multicenter setting. This type of technology can be an alternative option to a hospital-based setting or home care as it allows a lower burden for the patients and reduces the costs. The telerehabilitation approach is a promising, less invasive option that has the potential to improve patient care in a wider population in this setting.

Anonymous Patient Answer

Does multimodal teleprehabilitation improve quality of life for those with abdominal cancer?

Teleprehabilitation for cancer patients undergoing chemotherapy appears to improve a variety of QoL variables. Future research should determine the degree to which teleprehabilitation can decrease morbidity.

Anonymous Patient Answer

What is multimodal teleprehabilitation?

Data from a recent study shows that multimodal teleprehabilitation with [interdisciplinary] training enhances the ability of patients, families and GPs to cope better with the challenges of diagnosis, treatment and recovery.

Anonymous Patient Answer

What does multimodal teleprehabilitation usually treat?

Multimodal telespine rehabilitation can be highly specialized and helps patients with severe pain and also can help patients who suffer from other problems such as fatigue and depression and help to improve their self-esteem. The multimodal treatment of patients at a distance can be an effective method to increase patients' self-support. Multimodal telerehabilitation may be an effective tool for the education of telerehabilitation. The current findings provide new insights in this important area of research and will hopefully stimulate the further development of telerehabilitation in the future.

Anonymous Patient Answer
See if you qualify for this trial
Get access to this novel treatment for Thoracic Cancers by sharing your contact details with the study coordinator.