Enhanced Care for Smoking Cessation

Not currently recruiting at 5 trial locations
AA
KM
Overseen ByKenneth M Cummings, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Medical University of South Carolina
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores methods to help people quit smoking by testing two types of care: basic and enhanced. It targets hospitalized smokers who wish to stop smoking after discharge. The trial aims to determine if these care plans can improve outcomes in various hospital settings. Suitable candidates are hospitalized smokers who speak English and have a phone number for follow-up. As an unphased trial, it provides a unique opportunity for participants to contribute to innovative approaches in smoking cessation care.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that the Enhanced Care treatment for quitting smoking is generally safe. Studies have found that enhanced programs, which often include additional support or resources, help people stop smoking without major safety issues. Available information reports no serious side effects or problems linked to the Enhanced Care approach.

The Enhanced Care treatment aims to improve results by offering more support than basic care, such as counseling or digital tools. Participants in similar studies have successfully quit smoking, indicating that these programs are well-tolerated. While any new treatment carries some risk, evidence so far suggests that the Enhanced Care treatment is safe for those wanting to quit smoking.12345

Why are researchers excited about this trial?

Researchers are excited about the Enhanced Care for smoking cessation because it offers a more comprehensive approach compared to standard treatments like nicotine replacement therapies or medications such as varenicline and bupropion. Unlike these typical methods that focus mainly on reducing withdrawal symptoms, Enhanced Care may incorporate personalized support strategies, behavioral therapy, or digital tools to address the psychological and social aspects of quitting smoking. This holistic approach aims to improve long-term success rates by providing smokers with a more tailored support system, making it potentially more effective in helping individuals quit smoking for good.

What evidence suggests that this trial's treatments could be effective for smoking cessation?

Research has shown that improved care methods can significantly aid smoking cessation. In this trial, participants will join either the Enhanced Care Condition or the Basic Care Condition. For instance, one study found that nurse-led efforts increased the success rate of quitting by 43% after six months. Programs using digital tools, such as text messages, have proven even more effective, boosting quit rates by 63%. Additionally, comprehensive primary care programs increased quit rates from 1.3% to 8.7%. Overall, these enhanced care strategies, similar to the Enhanced Care Condition in this trial, are much more effective than basic care, which typically has lower success rates.678910

Who Is on the Research Team?

KM

Kenneth M Cummings, PhD

Principal Investigator

Medical University of South Carolina

Are You a Good Fit for This Trial?

This trial is for hospitalized cigarette smokers over the age of 18 who are being discharged back to their homes. Participants must have a phone number and be able to communicate in English. It's not open to those without a phone or who can't speak English.

Inclusion Criteria

discharged from the hospital back to their home
I am a hospitalized smoker eligible for care.
Discharged from the hospital back to their home
See 1 more

Exclusion Criteria

Patients without a phone number
I cannot communicate in English.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the opt-out MUSC-Tobacco Treatment Program during hospitalization

Duration of hospitalization

Follow-up

Participants are monitored for smoking behavior and use of cessation medication after discharge

6 weeks
Assessed post-discharge

What Are the Treatments Tested in This Trial?

Interventions

  • Basic Care
  • Enhanced Care
Trial Overview The study is testing two types of smoking cessation services: Basic Care and Enhanced Care, across different patient groups including psychiatric inpatients and non-psychiatric patients at various hospitals affiliated with MUSC.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Enhanced Care ConditionExperimental Treatment1 Intervention
Group II: Basic Care ConditionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Medical University of South Carolina

Lead Sponsor

Trials
994
Recruited
7,408,000+

Published Research Related to This Trial

The study evaluated an asynchronous smoking cessation e-visit for adult smokers in primary care, involving 51 participants, and found it to be acceptable and feasible, with high satisfaction rates among users.
The e-visit showed promising efficacy in improving smoking cessation outcomes compared to standard treatment, with participants having higher odds of quitting at both 1 month (ORs: 2.10-5.39) and 3 months (ORs: 1.31-4.67) post-enrollment.
Evaluation of a Proactive Smoking Cessation Electronic Visit to Extend the Reach of Evidence-Based Cessation Treatment via Primary Care.Dahne, J., Player, M., Carpenter, MJ., et al.[2022]

Citations

Effectiveness of nurse-initiated smoking cessation interventionThe OR for self-reported quit success 7-day smoking cessation rate at 6-month follow-up was 1.43 (95% CI [1.08, 1.90]), indicating a significant ...
A Review of Smoking Cessation Interventions - PubMed CentralMoreover, attempting to quit smoking without any structured approach yielded a mere 3%-5% success rate within the same timeframe [7]. This study ...
Efficacy of digital interventions for smoking cessation by ...SMS interventions demonstrated the highest efficacy (RR 1.63, 95% CI 1.38–1.92), indicating a 63% increased smoking cessation success compared ...
Cost-Effectiveness of a Comprehensive Primary Care ...Smoking cessation rates increased from 1.3% pre-implementation to 8.7% post-implementation, for an incremental effectiveness of 7.4%. The incremental cost ...
Enhanced vs Standard Varenicline Treatment for Tobacco ...Tobacco cessation rates at the 52-week follow-up were 25.1% (79 of 315 participants) for 12-week monotherapy, 24.4% (76 of 311) for 24-week ...
Public Health Impact of FDA's Request for Additional Safety ...We applied a 10% probability of smoking relapse after 1 year of abstinence. For life expectancy gains from smoking cessation at different ages ( ...
Public Health Impact of FDA's Request for Additional Safety ...In a mathematical model, making cytisine available immediately could lead approximately 71 000 more people to quit smoking over 1 year and ...
8.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/31240811/
Enhanced smoking cessation support for newly abstinent ...Measures: The primary outcome was self-reported continuous abstinence from smoking validated by an exhaled carbon monoxide level < 6 parts per million 4 weeks ...
HHS Framework to Support and Accelerate Smoking ...The HHS framework aims to support smoking cessation, reduce disparities, and enhance collaboration using a health equity lens, focusing on combusted tobacco ...
Digitally Enhanced Smoking Cessation for High Risk ...This is a research study, is testing a program to improve lung health through smoking cessation and providing education around lung screening.
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