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Peer-Driven Intervention for Substance Use (PROUD-R2 Trial)

N/A

Waitlist Available

Led By Todd Korthuis, MD, MPH

Research Sponsored by Oregon Health and Science University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

PROUD-R2 Trial Summary

This trial will test if a peer-driven intervention can help increase engagement in research among people who use drugs in rural America.

Who is the study for?

This trial is for adults over 18 living in the study area who currently inject drugs or use opioids to get high. It's also open to 'study buddies' from the same area, regardless of their substance use history, as long as they're adults.Check my eligibility

What is being tested?

The study is testing a peer-driven video intervention designed to help retain people who use drugs (PWUD) in rural research programs by leveraging peer influence and support.See study design

What are the potential side effects?

Since this trial involves a non-medical intervention (a retention video), there are no direct physical side effects expected from participating.

PROUD-R2 Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

12 Month Retention Rate

Secondary outcome measures

6 Month Retention Rate

PROUD-R2 Trial Design

2Treatment groups

Active Control

Group I: Standard Retention StrategyActive Control1 Intervention

Control arm: At NROI enrollment, all participants provide detailed information to assist with retention and/or contact for future research, and contact information for up to three people who should know how to reach the participant if contact information changes. Participants randomized to receive the standard retention strategy are contacted at the mid-point of each follow-up interval (i.e., at 3-month post enrollment and 9-months post-enrollment) to update locator information and remind them about their follow-up appointment date. Study associates contact the participant using their contact information and, if not successful, will try to reach one of their contacts in the locator form.

Group II: Retention VideoActive Control1 Intervention

Participants the peer-driven retention arm will receive video-based and in-person training from Retention Specialists on how to encourage study retention. Participants will watch a 7 minute video that standardizes retention messages. A brief face-to-face conversation with the Retention Specialist follows the video viewing to answer questions and reinforce video messages. At the end of the training, participants receive information about their recruit(s) who consented to release their information to their recruiters. Peers remind their enrolled "study buddy" to attend their scheduled follow up assessments. Participants meet with a study Retention Specialist by phone or in person, at 3 and 9 months after enrollment to answer questions about peer retention strategies and remind participants of their peers' contact information and follow-up schedules.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of KentuckyOTHER

185 Previous Clinical Trials

225,792 Total Patients Enrolled

1 Trials studying Substance Use

234 Patients Enrolled for Substance Use

Ohio State UniversityOTHER

828 Previous Clinical Trials

504,901 Total Patients Enrolled

6 Trials studying Substance Use

3,944 Patients Enrolled for Substance Use

Emory UniversityOTHER

1,636 Previous Clinical Trials

2,559,723 Total Patients Enrolled

2 Trials studying Substance Use

2,114 Patients Enrolled for Substance Use

Media Library

Retention Video Clinical Trial Eligibility Overview. Trial Name: NCT03885024 — N/A

Substance Use Research Study Groups: Standard Retention Strategy, Retention Video

Substance Use Clinical Trial 2023: Retention Video Highlights & Side Effects. Trial Name: NCT03885024 — N/A

Retention Video 2023 Treatment Timeline for Medical Study. Trial Name: NCT03885024 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants able to join this clinical research at the present moment?

"Clinicaltrials.gov indicates that this particular clinical trial is not presently recruiting participants, with its original posting on August 31st 2020 and final edit occurring on August 22nd 2022. However, 26 other medical studies are actively seeking to enrol patients at the moment."

Answered by AI

Recent research and studies

formation/NLM/NIH, NCBI. “Gprobe”. 2017. Web. <https://github.com/ncbi/gprobe>..Journal

Gprobe

Information/NLM/NIH, NCBI. 2017. “Gprobe”. GitHub repository. https://github.com/ncbi/gprobe.

clinicaltrials.govStudy

The Peer-Based Retention of People Who Use Drugs in Rural Research

P. Todd Korthuis, MD 2020. "The Peer-Based Retention of People Who Use Drugs in Rural Research". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03885024.