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Sciatic Nerve Block Techniques for ACL Injury Pain Control

N/A

Waitlist Available

Led By Jamie Furstein, CRNA

Research Sponsored by Children's Hospital Medical Center, Cincinnati

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Subject is scheduled for Unilateral ACL reconstruction with a hamstring autograft under general anesthesia on an outpatient basis, not in conjunction with any other surgical procedures

Subject is age 10 years to 18 years (inclusive)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 72 hours

Awards & highlights

Study Summary

This trial is testing if a single sciatic nerve block is better than a continuous one for pain control, active knee function, and patient satisfaction after ACL reconstruction with hamstring autograft.

Who is the study for?

Adolescents aged 10-18 scheduled for ACL reconstruction with hamstring autograft, without other surgeries or overnight hospital stays. They must be in good health (ASA I-II), have no allergies to local anesthetics, and not require preoperative sedation. Consent is needed from both the participant and a legal representative.Check my eligibility

What is being tested?

The study compares two pain control methods after ACL surgery: a single-injection sciatic peripheral nerve blockade (PNB) versus a continuous one. It measures post-op pain, knee movement, medication use, unplanned hospital visits due to pain, and patient satisfaction.See study design

What are the potential side effects?

Possible side effects include discomfort at injection site, potential nerve injury leading to weakness or numbness in the leg or foot area associated with the sciatic nerve distribution.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am scheduled for ACL surgery using my own tissue, without other surgeries.

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I am between 10 and 18 years old.

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I have agreed to nerve block anesthesia for my procedure.

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I am in good or mild systemic disease condition according to ASA.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 72 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~72 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 72 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Pain Reduction

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Continuous sciatic PNBExperimental Treatment1 Intervention

If a CPI catheter is placed, the CPI catheter will be placed under ultra-sound guidance, with the tip of the catheter being placed immediately adjacent to the sciatic nerve, after the local anesthesia has been deposited. CPI catheters will only remain in-situ for 48 hours.

Group II: Single-injection sciatic PNBActive Control1 Intervention

Under ultrasound-guidance, the sciatic nerve can readily be identified in the posterior thigh. The nerve appears hyperechoic and can be traced distally to the popliteal fossa, where it divides into the tibial and common peroneal nerves. Local anesthesia is injected under real-time visualization following a negative aspiration. If a single-injection block is done, local anesthesia is deposited adjacent to the sciatic nerve within the fascial plane, but not within the epineurium. As such, single-injection sciatic PNB, which can last up to 24 hours, should provide adequate analgesia precluding the need for oral narcotic or nonsteroidal anti-inflammatory medications following ACL reconstruction with a hamstring autograft.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Continuous sciatic PNB

2015

N/A

~150

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Children's Hospital Medical Center, CincinnatiLead Sponsor

815 Previous Clinical Trials

6,531,455 Total Patients Enrolled

Jamie Furstein, CRNAPrincipal InvestigatorAANA Foundation

1 Previous Clinical Trials

79 Total Patients Enrolled

Media Library

Continuous sciatic PNB Clinical Trial Eligibility Overview. Trial Name: NCT02947633 — N/A

Anterior Cruciate Ligament Injury/Tear Research Study Groups: Single-injection sciatic PNB, Continuous sciatic PNB

Anterior Cruciate Ligament Injury/Tear Clinical Trial 2023: Continuous sciatic PNB Highlights & Side Effects. Trial Name: NCT02947633 — N/A

Continuous sciatic PNB 2023 Treatment Timeline for Medical Study. Trial Name: NCT02947633 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies remaining to join this experiment?

"As indicated by the clinicaltrials.gov website, this particular trial is not presently enrolling patients. The research was initially uploaded on March 1st 2015 and its last update occurred on August 3rd 2021. Nevertheless, two other studies are currently recruiting test subjects as of now."

Answered by AI

Do I meet the qualifications to participate in this clinical investigation?

"This clinical investigation is searching for 140 minors (ages 10 to 18) with anterior cruciate ligament tears. The eligible applicant must identify as male or female, come from any racial group, and agree to undergo unilateral ACL reconstruction surgery under general anesthesia on an outpatient basis without additional procedures alongside it. Furthermore, they should also provide consent for femoral and sciatic peripheral nerve blockade which needs to be obtained by a certified medical practitioner such as Mds, DOs, CRNAs or APNs."

Answered by AI