← Back to Search

Dietary Supplement

Choline for Cardiovascular Risk

N/A

Waitlist Available

Led By Kevin Davy, PhD

Research Sponsored by Virginia Polytechnic Institute and State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3-hour test in laboratory at 4 timepoints; baseline, week 4, week 6, and week 10

Awards & highlights

Study Summary

This trial is looking at whether a metabolite produced by gut microbes, Trimethylamine-N-oxide (TMAO), is linked to increased risk of cardiovascular disease in humans. They will be supplementing participants with dietary choline to see if it has any effect on cardiovascular disease risk factors.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3-hour test in laboratory at 4 timepoints; baseline, week 4, week 6, and week 10

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3-hour test in laboratory at 4 timepoints; baseline, week 4, week 6, and week 10

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3-hour test in laboratory at 4 timepoints; baseline, week 4, week 6, and week 10 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Insulin Sensitivity after Supplementation

Secondary outcome measures

Glucose

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Choline supplementationActive Control1 Intervention

Participants will consume 1000 mg of choline per day for 4 weeks.

Group II: Placebo supplementationPlacebo Group1 Intervention

Participants will consume 1000 mg of placebo per day for 4 weeks.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Virginia Polytechnic Institute and State UniversityLead Sponsor

141 Previous Clinical Trials

27,750 Total Patients Enrolled

3 Trials studying Cardiovascular Risk

60 Patients Enrolled for Cardiovascular Risk

Kevin Davy, PhDPrincipal Investigator - Virginia Polytechnic Institute & State University

Virginia Polytechnic Institute and State University

4 Previous Clinical Trials

102 Total Patients Enrolled

3 Trials studying Cardiovascular Risk

60 Patients Enrolled for Cardiovascular Risk

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals aged 35 or older eligible to participate in this experiment?

"As established in the criteria for this research endeavour, participants must be under 79 years old and above 18."

Answered by AI

How many participants will be involved in this clinical trial?

"Affirmative. Information hosted on clinicaltrials.gov confirms that this medical trial, which was initially published on December 15th 2020, is currently seeking participants. Approximately 60 individuals are required to be recruited from a solitary medical facility."

Answered by AI

Is recruitment for this medical trial happening at present?

"Affirmative. The data hosted on clinicaltrials.gov shows that this experiment, initially advertised on December 15th 2020, is presently accepting participants. Approximately 60 volunteers need to be recruited from 1 centre."

Answered by AI

Is it possible for me to sign up and participate in this medical research?

"Patients with a history of cardiovascular risk can participate in this trial, provided they are aged between 18 and 79. Currently, there is an effort to recruit 60 participants for the study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Choline and Cardiometabolic Health

Kevin Davy 2021. "Choline and Cardiometabolic Health". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04764162.