← Back to Search

low FODMAP diet for Small Intestinal Bacterial Overgrowth

N/A

Waitlist Available

Research Sponsored by Beth Israel Deaconess Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Aged 18-65 years at the time of screening

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 weeks

Awards & highlights

Study Summary

This trial found that bloating is a common symptom of IBS, which affects 11% of people worldwide. SIBO is a potential cause of bloating and is present in 78% of IBS patients. After antibiotic therapy, 48% of patients no longer had IBS. Further studies are needed to understand how FODMAPs affect intestinal permeability and microbiome.

Who is the study for?

This trial is for adults aged 18-65 who experience bloating and meet the criteria for functional bowel disorders like IBS. They must have a specific score indicating severe symptoms on an IBS symptom scale and test positive for SIBO.Check my eligibility

What is being tested?

The study is testing whether a low FODMAP diet, which limits certain carbohydrates believed to cause discomfort, can improve symptoms in people with Small Intestinal Bacterial Overgrowth (SIBO) associated with IBS.See study design

What are the potential side effects?

A low FODMAP diet may lead to changes in diet-related habits and could potentially result in nutritional deficiencies if not properly managed. However, it's generally considered safe with guidance from healthcare professionals.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 65 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ three weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~three weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and three weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

SIBO diagnosis

Secondary outcome measures

IBS-SSS

Rome IV Functional Bloating diagnostic criteria

Other outcome measures

serum LPS level

serum zonulin level

Trial Design

1Treatment groups

Experimental Treatment

Group I: low FODMAP dietExperimental Treatment1 Intervention

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Beth Israel Deaconess Medical CenterLead Sponsor

836 Previous Clinical Trials

13,010,200 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any opportunities for participation in this research still available?

"Based on the records available at clinicaltrials.gov, this research project has concluded its recruitment phase. The study was initially listed on November 15th 2020 and last modified December 6th 2023; however, there are 3 other ongoing medical trials that require volunteers presently."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effect of a Low FODMAP Diet on SIBO

Judy Nee 2020. "Effect of a Low FODMAP Diet on SIBO". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04627727.

All > Sibo