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ESP with Bupivacaine 0.5% for Video-assisted Thoracoscopic Surgery

N/A

Waitlist Available

Led By Ariane Clairoux, MD

Research Sponsored by Ciusss de L'Est de l'Île de Montréal

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up intraoperatively

Awards & highlights

Study Summary

Erector spinae (ESP) block is a recently described plane block designed to block the dorsal and ventral rami of the thoracic spinal nerves. It is meant to block the ipsilateral trunk. The aim of the study is to demonstrate the efficacy of the ESP block as postoperative analgesia for VATS surgery.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ pre and postoperatively

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~pre and postoperatively

This trial's timeline: 3 weeks for screening, Varies for treatment, and pre and postoperatively for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Postoperative hydromorphone consumption

Secondary outcome measures

Amount of intraoperative Fentanyl use

Global QoR-15 score : 0 to 150 (worst to best)

PONV Score : 1 to 3 (1- No nausea, 2- Nausea, 3- Vomiting)

+3 more

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: ESP with Bupivacaine 0.5%Active Control1 Intervention

The Erector Spinae Block (ESP) will be performed using the method described by Forero et al and Hamilton et al. in 2017 by an expert regional anesthesiologist. Thirty milliliters of bupivacaine at a concentration of 0.5% with epinephrine 1:200 000 will be injected depending on the patient's allocation. Patient controlled analgesia (PCA) settings for both groups will remain the same: hydromorphone with a bolus of 0,2 mg, lockout time of 5 minutes and no background infusion. The PCA will be started when the patient is transferred to the postanesthesia care unit (PACU).

Group II: ESP with Saline 0.9%Placebo Group1 Intervention

The Erector Spinae Block (ESP) will be performed using the method described by Forero et al and Hamilton et al. in 2017 by an expert regional anesthesiologist. Thirty milliliters of a placebo solution (normal saline) will be injected depending on the patient's allocation. Patient controlled analgesia (PCA) settings for both groups will remain the same: hydromorphone with a bolus of 0,2 mg, lockout time of 5 minutes and no background infusion. The PCA will be started when the patient is transferred to the postanesthesia care unit (PACU).

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