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Radiofrequency Ablation for Thyroid Cancer

Phase 1

Waitlist Available

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Cytologically confirmed papillary thyroid cancer by fine needle aspiration

Requires thyroidectomy

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Study Summary

This trial is testing the use of radiofrequency ablation to treat thyroid cancer. The purpose is to study the side effects of this treatment.

Who is the study for?

This trial is for adults over 21 with low-risk, papillary thyroid cancer confirmed by needle aspiration. Participants should have a single tumor no larger than 1.5 cm located in the front two-thirds of the thyroid and not next to the trachea, without lymph node involvement or multicentric tumors.Check my eligibility

What is being tested?

The study is testing radiofrequency ablation (RFA), which uses high-frequency electric currents to destroy tumor cells before surgery. The RFA is guided by ultrasound to target thyroid cancer effectively.See study design

What are the potential side effects?

Potential side effects of radiofrequency ablation may include pain at the treatment site, swelling, bruising, changes in voice if nerves are affected, and infection risk. These are generally mild but can vary based on individual response.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My thyroid cancer was confirmed with a needle biopsy.

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I need surgery to remove my thyroid.

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I do not have swollen lymph nodes in my neck.

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My cancer has not spread to my lymph nodes.

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My thyroid tumor is small, not near my windpipe, and located in the front part of my thyroid.

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My disease is considered low-risk and does not have aggressive cell types.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Frequency of radiofrequency ablation-associated complications at 2 weeks

Secondary outcome measures

Amount of tumor destruction at 2 weeks

0 / 6Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor

2,505 Previous Clinical Trials

15,237,555 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,663 Previous Clinical Trials

40,925,905 Total Patients Enrolled

Electron Kebebew, MDStudy ChairUniversity of California, San Francisco

4 Previous Clinical Trials

530 Total Patients Enrolled

Media Library

Treatment Clinical Trial Eligibility Overview. Trial Name: NCT00103155 — Phase 1

Head and Neck Cancers Research Study Groups:

Head and Neck Cancers Clinical Trial 2023: Treatment Highlights & Side Effects. Trial Name: NCT00103155 — Phase 1

Treatment 2023 Treatment Timeline for Medical Study. Trial Name: NCT00103155 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What risks might be associated with this treatment regimen?

"A rating of 1 was assigned to this treatment due to the fact that it is a Phase 1 trial, meaning there are limited data available on its safety and efficacy."

Answered by AI

Is there still capacity to enroll participants in this research endeavor?

"Clinicaltrials.gov confirms that this study, originally posted on September 1st 2004 and last updated on September 19th 2013, is not presently recruiting patients. Although the trial has concluded its recruitment period, 476 other medical studies are still open to participants at present."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Radiofrequency Ablation in Treating Patients Who Are Undergoing Surgery for Thyroid Cancer

2004. "Radiofrequency Ablation in Treating Patients Who Are Undergoing Surgery for Thyroid Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00103155.

All > Thyroid Cancer > Thyroid