149 Participants NeededMy employer runs this trial

E303 for Cancer

SB
Overseen BySamsung Bioepis
Age: 18+
Sex: Any
Trial Phase: Phase 1
Sponsor: Samsung Bioepis Co., Ltd.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This is a Phase I trial to evaluate the safety, tolerability and efficacy of nectin-4 targeting antibody-drug conjugate (SBE303) in participants with advanced solid tumors

Are You a Good Fit for This Trial?

Inclusion Criteria

My advanced or metastatic cancer has come back or worsened after standard treatment.

Exclusion Criteria

Have an active autoimmune disease
I have cancer that has spread to the lining of my brain or spinal cord.
I have serious heart or blood vessel disease.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the nectin-4 targeting antibody-drug conjugate (SBE303) for safety and efficacy evaluation

32 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • E303

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: E303Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Samsung Bioepis Co., Ltd.

Lead Sponsor

Trials
32
Recruited
9,900+