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Cancer Vaccine
Vaccine Therapy for Prostate Cancer
Phase 1
Waitlist Available
Research Sponsored by Jonsson Comprehensive Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Age: 18 and over
Limited bone disease with no more than 3 metastatic sites on bone scan and minimal symptoms
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
Study Summary
This trial is studying a vaccine made from a person's own blood cells. The vaccine is being given to see if it will help to control metastatic prostate cancer.
Who is the study for?
This trial is for adults with metastatic prostate cancer that hasn't improved with hormone therapy. They should have limited bone disease, no brain tumors, and a rising PSA level or new symptoms like bone pain. Men must not be expected to live less than a year, have severe blood, liver, kidney issues or uncontrolled diseases.Check my eligibility
What is being tested?
The study tests vaccine therapy using the patient's own stem cells to prompt the body to attack prostate cancer cells. It's in Phase I to see how well it works for those whose cancer has spread and isn't responding to hormones.See study design
What are the potential side effects?
Potential side effects aren't specified here but may include typical vaccine reactions such as soreness at injection site, fever, fatigue or allergic responses given it’s an immune system-based treatment.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 18 years old or older.
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My cancer has spread to no more than 3 places in my bones and I have few symptoms.
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I have new bone pain or a new finding on a bone scan.
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My prostate cancer has spread and does not respond to hormone therapy.
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I am fully active or able to carry out light work.
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My kidney function is good, with creatinine levels low and no uncontrolled kidney disease.
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My testosterone levels are low due to treatment.
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My soft tissue cancer has worsened, as shown by CT or MRI.
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My cancer has not spread to my brain.
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My liver functions are normal, I don't have hepatitis, and my liver disease is under control.
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My heart condition is under control.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
Treatment Details
Find a Location
Who is running the clinical trial?
Jonsson Comprehensive Cancer CenterLead Sponsor
359 Previous Clinical Trials
26,075 Total Patients Enrolled
38 Trials studying Prostate Cancer
4,000 Patients Enrolled for Prostate Cancer
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,933,153 Total Patients Enrolled
560 Trials studying Prostate Cancer
507,173 Patients Enrolled for Prostate Cancer
Arie Belldegrun, MD, FACSStudy ChairJonsson Comprehensive Cancer Center
7 Previous Clinical Trials
1,102 Total Patients Enrolled
5 Trials studying Prostate Cancer
221 Patients Enrolled for Prostate Cancer
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have not had my spleen removed.I am continuing hormonal therapy, except for antiandrogens like LHRH.I am 18 years old or older.My cancer has spread to no more than 3 places in my bones and I have few symptoms.I have taken antibiotics for minor infections no more than twice in the last 45 days.I have new bone pain or a new finding on a bone scan.I have never taken ketoconazole.My prostate cancer has spread and does not respond to hormone therapy.I haven't had radiation for cancer that has spread, including with strontium chloride Sr 89.It has been over 4 weeks since I last took immunosuppressive medication.I am not on any medication that affects my immune system, except for over-the-counter pain relievers, low-dose antihistamines, vitamins, or H2 blockers.I am fully active or able to carry out light work.My kidney function is good, with creatinine levels low and no uncontrolled kidney disease.I have no severe allergies, immune diseases, a negative TB skin test, and I am HIV negative.My PSA levels have increased by 50% from the lowest point, confirmed twice.My testosterone levels are low due to treatment.My soft tissue cancer has worsened, as shown by CT or MRI.My cancer has not spread to my brain.My treatment plan for biologic therapy is not decided.My liver functions are normal, I don't have hepatitis, and my liver disease is under control.I haven't had chemotherapy for cancer that has spread.I don't have spinal cord issues, serious illnesses, or recent cancers except for treated skin cancer.My heart condition is under control.
Research Study Groups:
This trial has the following groups:Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Does this research endeavor still accept participants?
"According to the listing on clinicaltrials.gov, this medical study is no longer recruiting individuals for participation as it was initially posted in December 2000 and last updated in August 2013. However, there are still 1,321 other studies that require patient enrolment at present."
Answered by AI
Has this treatment been authorized by the FDA?
"The safety rating for this treatment is estimated to be a 1 since we are only in the initial stages of clinical trials. This implicates that there is minimal data backing its efficacy and security."
Answered by AI
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