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Hormone Therapy

Intranasal Oxytocin for Opioid Addiction

Phase 1

Waitlist Available

Research Sponsored by MacDonald, Kai, M.D.

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Adult men 18 years or older

Negative salivary drug screen, save for opiates

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 minutes

Awards & highlights

Study Summary

This trial will test whether oxytocin can help people with opiate dependence by improving their emotional processing and stress responses.

Who is the study for?

This trial is for adult men aged 18 or older with opiate dependence who can use a nasal spray, have been abstinent from non-prescribed opiates for at least two weeks, and are clinically stable. They must not have any other active substance dependence (except nicotine) or severe mental illnesses.Check my eligibility

What is being tested?

The study tests intranasal oxytocin's effects on emotional processes and stress responses in patients with opioid addiction. The hypothesis suggests that oxytocin could improve brain-based functions related to emotion and stress in these individuals.See study design

What are the potential side effects?

While the side effects of intranasal oxytocin aren't detailed here, common ones may include irritation at the application site, headache, changes in heart rate or blood pressure, nausea, fatigue, and emotional changes.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am a man aged 18 or older.

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My drug test is clean except for prescribed pain medication.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 minutes

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 minutes

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Cold Pressor Task

Trial Design

1Treatment groups

Experimental Treatment

Group I: oxytocinExperimental Treatment1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Oxytocin

FDA approved

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

MacDonald, Kai, M.D.Lead Sponsor

1 Previous Clinical Trials

18 Total Patients Enrolled

Media Library

Oxytocin (Hormone Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT02052258 — Phase 1

Opioid Addiction Research Study Groups: oxytocin

Opioid Addiction Clinical Trial 2023: Oxytocin Highlights & Side Effects. Trial Name: NCT02052258 — Phase 1

Oxytocin (Hormone Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02052258 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new recruits still being welcomed into this experiment?

"This research project, which was initially posted on January 1st 2013 and last modified on September 11th 2014, is not currently enrolling patients. However, there are other clinical trials open for participation at this time with a total of 344 active postings."

Answered by AI

For what clinical purposes is Oxytocin commonly employed?

"Oxytocin is routinely used to manage excessive bleeding. Additionally, it can be employed in the management of labour and uterine contractions as well as for bolstering delivery."

Answered by AI

Has Oxytocin been given the green light by the Food and Drug Administration?

"As Oxytocin is currently being tested in a Phase 1 trial, meaning there are limited data validating its safety and efficacy, our team gave it a rating of 1 on the scale."

Answered by AI

What is the maximum number of participants for this experimentation?

"Currently, this trial is not enrolling participants. It was first uploaded on January 1st 2013 and last updated September 11th 2014. For those looking for other options, 291 studies related to opioid abuse are actively recruiting at present along with 53 trials dealing with Oxytocin that require patients."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Oxytocin in Opiate Dependence: A Pilot Study of the Effects of Intranasal Oxytocin on Emotional Processes and Stress Responses in Patients With Opiate Dependence

2013. "Oxytocin in Opiate Dependence: A Pilot Study of the Effects of Intranasal Oxytocin on Emotional Processes and Stress Responses in Patients With Opiate Dependence". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02052258.

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