Study Summary
This trial is testing isatuximab given with carfilzomib, with or without dexamethasone and lenalidomide, to see what effects, good and bad, it has in treating patients with multiple myeloma that has come back or did not respond to previous treatment.
- Multiple Myeloma
Treatment Effectiveness
Effectiveness Progress
Study Objectives
3 Primary · 10 Secondary · Reporting Duration: assessed at 1, 2, and 3 years from start of treatment
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Arm II (40 mg dexamethasone, isatuximab, carfilzomib)
1 of 2
Arm I (20 mg dexamethasone, isatuximab, carfilzomib)
1 of 2
Experimental Treatment
89 Total Participants · 2 Treatment Groups
Primary Treatment: Carfilzomib · No Placebo Group · Phase 1
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 10 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Has the Food and Drug Administration given its blessing to Carfilzomib?
"Carfilzomib's safety is assessed as a 1 on our rating scale, indicating that there are only limited data points to suggest efficacy and drug security." - Anonymous Online Contributor
Are there still openings available to enrollees in this trial?
"Clinicaltrials.gov demonstrates that this healthcare research is still in the recruitment phase, with a first posting date of January 21st 2015 and an edit as recent as July 3rd 2022." - Anonymous Online Contributor
What indications is Carfilzomib typically employed to treat?
"Carfilzomib is typically given to those suffering from ophthalmia and sympathetic. This medication can also be used to treat branch retinal vein occlusion, macular edema, as well as communicable illnesses." - Anonymous Online Contributor
What other researches have been conducted regarding Carfilzomib?
"Presently, 579 medical trials are underway for Carfilzomib, with 146 of those being in the third stage. A majority of these studies take place near Mishawaka, Indiana; however 19278 other sites around the world have clinical research projects dedicated to this drug's efficacy." - Anonymous Online Contributor
Is this research endeavor being implemented in various healthcare establishments across the US?
"This research project is being administered at a quartet of clinical sites, such as the University of California in San Francisco, Icahn School of Medicine situated in New York City, Hackensack University Medical Center located near Hackensack and 4 other associated medical facilities." - Anonymous Online Contributor
What is the current size of this trial's participant base?
"Affirmative. Clinicaltrials.gov reveals that this clinical trial is open for recruitment, having first been posted on January 21st 2015 and last updated July 3rd 2022. The research requires 89 participants to be sourced from four sites." - Anonymous Online Contributor