VB10.NEO for Solid Tumors, Adult

"Can cancer be cured? answer: The possibility of cure for a wide range of solid tumours has not been proven. The use of surgery alone is often inadequate due to the development of metastatic disease that can be treated with chemotherapy or radiotherapy. The ability of cancer to form new tumours despite treatment is also a difficult problem in cancer surgery, and warrants future effort to find effective approaches to preventing this problem." - Anonymous Online Contributor

"Few individuals diagnosed with cancer receive treatment solely based on medical criteria. A minority of patients in this study received no treatments or therapies. In the absence of clinical trials to define optimal treatments, medical practitioners sometimes decide more on clinical judgment than on objective criteria. Future interventions to increase the use of effective therapies should focus on reducing unnecessary diagnostic tests and tests of nonspecific clinical value, improving cancer education, promoting optimal cancer screening, and identifying patients most likely to benefit from adjuvant therapies." - Anonymous Online Contributor

"Cancer typically presents with a sudden painless enlargement of the size and/or the girth of one or both sides of the body, and sometimes, the head or neck, due to lymphocytic infiltration and/or metastasis.\n" - Anonymous Online Contributor

"This definition of cancer is the most widely used in the field. It is useful when it is applied to specific and individual cancers. The general consensus is that the word "cancer" should only be substituted when the medical term is available, or where no better term exists. In the latter case, and in clinical practice, the word should be restricted to synonymous expressions when a generic term is used, as in 'disease of the body organs', 'disease of the respiratory tract', or 'disease of the eye'." - Anonymous Online Contributor

"Approximately 6.6 million people (5.5% of the population) are diagnosed with cancer a year in the United States. There are roughly 240,000 new cancer diagnoses per year. The burden of non-melanoma skin cancer is higher than for melanoma. There are about 80,000 new cases of head and neck cancer, 50,000 new cases of breast cancer, 45,000 new cases of colorectal cancer and 38,000 new cases of cervical cancer. Cancer incidence, stage of presentation and survival are worse for people with limited or unspecified limitation in daily functioning. Cancer mortality for the total population is falling, but worse in non-Hispanic black men aged 85 or older (23." - Anonymous Online Contributor

"Approximately 17% of the world's population dies of malignant disease of the breast, colon, prostate, lung or kidney. Most cancers can be diagnosed only after many years. What causes cancer? A number of factors contribute to the development of cancer. This may be through inherited or acquired factors, such as viruses, bacteria, DNA damage, toxins, genetic and environmental factors. A common link or link in causation may exist between cancer and viruses, and, to a lesser extent, some environmental factors. The mechanism of causation for cancer is highly complex and requires a multidisciplinary approach to be understood. It is important to examine both current and historic information on the subject to gain a wider understanding and hopefully improve patient management." - Anonymous Online Contributor

"The expression of the Vb10 gene by the host is upregulated by HBV to enhance the replication of HBV on the hepatocyte. HBV may also induce the production of a new and unique small RNA molecule named vb10.neo. The vb10.neo siRNA inhibits expression of Vb10 gene to a great extent and reduces the hepatitis B virus DNA in vitro." - Anonymous Online Contributor

"The association between lifestyle risk factors and the development of cancers is well-known among the general population. More recently, genetic predisposition is added to the list of factors that may cause cancer. As our understanding of the aetiology expands, it is possible that in some circumstances, cancer can be caused by a complex mixture of genetic and environmental risk factors. Therefore, how the cause of cancer affects the phenotype (i.e. how it manifests itself and where it spreads) is a crucial aspect of the emerging research on cancer." - Anonymous Online Contributor

"In the Western world, the average age of people diagnosed with cancer is aged 60 years, with a range of 49 to 69 years for males and 51 and 69 years for females. It does seem to reflect the typical age at which cancer is normally diagnosed. The overall age at which cancer is diagnosed appears to be rising in the UK." - Anonymous Online Contributor

"Data from a recent study suggest that the effect of VVb10.neo is related to the inhibition of collagen synthesis, which is the main process of tumor growth." - Anonymous Online Contributor

"Every cancer has some very serious risks. The most serious risks are that of the underlying disease that starts the cancer in the first place (especially if not treatable), that the cancer spreads around the body, and that, if there's a cure or even a good treatment, it may become more dangerous as many of the side effects of the treatment may become apparent (which is known as a drug effect). However, many cancer patients cope with all these factors happily and get on with their lives without the need for serious thinking about the risks. Many don't need to." - Anonymous Online Contributor

"Cancer family history can be identified in a family even when many of the members do not have diagnosed disease. This finding suggests that an emphasis should be placed on implementing family education programs for those affected by cancer and early identification of family members with a family history of cancer will help minimize the occurrence of illness in future generations. This is the first study to show that cancer cases in a given population are familial" - Anonymous Online Contributor