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Immunotherapy

ALPN-202 for Lymphoma (NEON-1 Trial)

Phase 1
Waitlist Available
Research Sponsored by Alpine Immune Sciences, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 30 days after last dose of study drug
Awards & highlights

NEON-1 Trial Summary

This trial is testing a new cancer treatment in adults with advanced solid tumors or lymphoma that have not responded to other treatments or for whom there is no standard or curative therapy available.

Eligible Conditions
  • Solid Tumors
  • Lymphoma

NEON-1 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 30 days after last dose of study drug
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 30 days after last dose of study drug for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Adverse Events
Secondary outcome measures
Objective response

NEON-1 Trial Design

1Treatment groups
Experimental Treatment
Group I: Dose escalation and expansionExperimental Treatment1 Intervention
ALPN-202

Find a Location

Who is running the clinical trial?

Alpine Immune Sciences, Inc.Lead Sponsor
8 Previous Clinical Trials
524 Total Patients Enrolled
1 Trials studying Lymphoma
29 Patients Enrolled for Lymphoma
Stanford Peng, MD PhDStudy DirectorAlpine Immune Sciences
1 Previous Clinical Trials
72 Total Patients Enrolled
Zelanna Goldberg, MDStudy DirectorAlpine Immune Sciences, Inc.

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What criteria must participants satisfy to be accepted into this clinical trial?

"This clinical trial seeks 62 individuals between the ages of 18 and 75 who have lymphoma. Participants must also meet further conditions, including but not limited to: having an adult age at screening from 18-75 years old; a histologically ascertained inoperable solid tumor that is either resistant or refractory to standard treatments such as checkpoint inhibitors if applicable; metastatic cutaneous melanoma; PD-L1 positive cancers aside from cutaneous melanoma or renal cell carcinomatous cells; and measurable disease according to protocol requirements."

Answered by AI

Is the minimum age requirement for this investigation over 25?

"This trial seeks participants who are of legal age and no older than 75 years old."

Answered by AI

How many locations are participating in the trial's implementation?

"14 different clinical sites are participating in this trial, with locations ranging from Scottsdale to Lafayette. It is advised that one selects the nearest option available to minimize their travel obligations if they choose to participate."

Answered by AI

What potential risks have been associated with ALPN-202?

"We have assigned ALPN-202 a score of 1 on our safety scale due to the fact that this is only a Phase 1 trial, meaning there are limited clinical studies assessing its efficacy and safety."

Answered by AI

Are participants still enrolling for this experiment?

"Clinicaltrials.gov demonstrates that this trial, initially posted on June 2nd 2020, is no longer looking for participants. However, there are currently 4061 other clinical studies actively recruiting patients."

Answered by AI
~13 spots leftby Apr 2025