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Cancer Vaccine

Helixor® M for Solid Tumors

Phase 1
Waitlist Available
Led By Channing Paller, MD
Research Sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Any patients who have had any prior treatment with Mistletoe (injection or infusion) will not be eligible for this study.
Age >18 years.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 years
Awards & highlights

Study Summary

This trial will study the effects of Helixor® M, a possible cancer treatment, in patients with advanced solid tumors. The goal is to find the maximum tolerated dose and to learn more about the safety and side effects of the drug.

Eligible Conditions
  • Solid Tumors

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Maximum tolerated dose (MTD)
Number of participants experiencing toxicities
Secondary outcome measures
Tumor marker kinetics

Trial Design

1Treatment groups
Experimental Treatment
Group I: Helixor® MExperimental Treatment1 Intervention
Advanced solid tumors
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Helixor® M
2017
Completed Phase 1
~30

Find a Location

Who is running the clinical trial?

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsLead Sponsor
556 Previous Clinical Trials
32,845 Total Patients Enrolled
Believe BigUNKNOWN
Channing Paller, MDPrincipal InvestigatorSidney Kimmel Comprehensive Cancer Center at Johns Hopkins
5 Previous Clinical Trials
653 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has this type of study been conducted previously?

"To date, 225 clinical trials for Helixor® M have been initiated in 2395 cities and 74 nations. The first of these studies was sponsored by Genzyme (a Sanofi Company) back in 2007 with 698 participants; it culminated into a Phase 3 drug approval stage. In the 14 years since then, 297 further such investigations have taken place."

Answered by AI

Who is the intended population for enrollment in this investigation?

"This clinical trial is seeking 58 participants with a malignancy aged between 18 and 100. To qualify, applicants must have not previously been exposed to mistletoe therapy, received first-line systemic treatment for metastatic disease that has either progressed or become refractory due to toxicities (other cases may be considered on an individual basis), demonstrate measurable lesions according to RECIST 1.1 criteria, have ECOG performance status of 0-2, life expectancy of greater than 3 months, WBC ≥3 000/mcL Absolute neutrophil count ≥1000/mcL Platelets ≥90 000/mcL Hemoglobin ≥9"

Answered by AI

What medical issues does Helixor® M offer remediation for?

"Helixor® M is generally prescribed to those suffering from ovarian cancer, however it can also be utilized to address unresectable thymoma, locally advanced nonsquamous non-small cell lung cancer, and mesotheliomas."

Answered by AI

Are geriatric patients being considered for this experiment?

"This medical trial is available to patients between the ages of 18-100, as per the defined eligibility requirements."

Answered by AI

Are there current vacancies available for patients to join this clinical trial?

"It appears that clinicaltrials.gov does not currently list this trial as actively recruiting participants; the study was first published on March 1st 2017 and last edited on October 31st 2022. Although this particular study is inactive, there are 2810 other active studies looking for volunteers at present."

Answered by AI

How many participants are involved in this medical experiment?

"This research program is no longer enrolling participants, with the last update to its listing occurring on October 31st 2022. If you are searching for other studies, there are 2585 active cancer-focused trials and 225 seeking patients for Helixor® M treatments available presently."

Answered by AI

Is there a body of evidence attesting to the efficacy of Helixor® M?

"Presently, 225 active trials are being conducted to evaluate the efficacy of Helixor® M. Of these studies, 87 have progressed to Phase 3 and are taking place across 19466 different medical sites; most of which can be found in Winston-Salem, North carolina."

Answered by AI

What are the likely risks associated with Helixor® M usage?

"With limited clinical data in regards to safety and efficacy, Helixor® M only received a score of 1."

Answered by AI
~3 spots leftby Apr 2025