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N-acetylcysteine 2400mg X Cue Exposure (marijuana) for Cannabis Abuse (MCN Trial)

Phase 1
Waitlist Available
Led By Leslie Lundahl, PhD
Research Sponsored by Wayne State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change is being assessed. marijuana craving vas administered at baseline 0900, at 0930, 1000, 1030, 1100, 1230, 1250, 1310, 1320, 1330, 1345, 1400, 1430, 1500, 1530, and 1600.
Awards & highlights

MCN Trial Summary

This trial will study whether being reminded of marijuana (cues) affects people's craving for it and whether a drug called N-acetylcysteine can help to reduce craving or use.

MCN Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change is being assessed. marijuana craving vas administered at baseline 0900, at 0930, 1000, 1030, 1100, 1230, 1250, 1310, 1320, 1330, 1345, 1400, 1430, 1500, 1530, and 1600.
This trial's timeline: 3 weeks for screening, Varies for treatment, and change is being assessed. marijuana craving vas administered at baseline 0900, at 0930, 1000, 1030, 1100, 1230, 1250, 1310, 1320, 1330, 1345, 1400, 1430, 1500, 1530, and 1600. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Core-body temperature (physiological effects)
Diastolic blood pressure (physiological effects)
Heart rate (physiological effects)
+8 more

MCN Trial Design

4Treatment groups
Active Control
Placebo Group
Group I: N-acetylcysteine 2400mg X Cue Exposure (marijuana)Active Control1 Intervention
Group II: N-acetylcysteine 2400mg X Cue Exposure (neutral)Active Control1 Intervention
Group III: N-acetylcysteine 0mg X Cue Exposure (marijuana)Placebo Group1 Intervention
Group IV: N-acetylcysteine 0mg X Cue Exposure (neutral)Placebo Group1 Intervention

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Who is running the clinical trial?

Wayne State UniversityLead Sponsor
307 Previous Clinical Trials
108,443 Total Patients Enrolled
Leslie Lundahl, PhDPrincipal InvestigatorWane State University
5 Previous Clinical Trials
334 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Marijuana Cue-Reactivity & Seeking Behavior in Regular Cannabis Users
Leslie Lundahl 2017. "Marijuana Cue-Reactivity & Seeking Behavior in Regular Cannabis Users". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03154580.
~3 spots leftby Apr 2025
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