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Everolimus for Lymphoblastic Leukemia (ENCERT Trial)
ENCERT Trial Summary
This trial is testing a new cancer drug, everolimus, to see what the maximum tolerated dose is when used with standard chemotherapy for T-cell leukemia/lymphoma.
- Lymphoblastic Leukemia
- Lymphoblastic Lymphoma
ENCERT Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2017 Phase 4 trial • 60 Patients • NCT02096107ENCERT Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Are there numerous locations administering this trial within the state?
"Currently, the trial is accepting patients at four locations: New york, Cincinnati and Atlanta among others. To reduce travel demands associated with participation in this study, it's important to register at a medical center close to you."
What medical conditions commonly prompt a prescription for Everolimus?
"Everolimus is a commonly prescribed treatment for leukemia and has shown to be successful in mitigating refractory advanced renal cell carcinoma, prostate cancer, and lung cancers."
How many participants are being welcomed into this medical study?
"Affirmative. The information posted on clinicaltrials.gov reveals that this research endeavour, which was first introduced on July 24th 2018 is currently searching for participants. A total of 15 individuals are expected to enrol from across 4 distinct centres."
Are there any recorded attempts to use Everolimus for medical purposes in the past?
"Everolimus was first studied in 1997 at the City of Hope Comprehensive Cancer Center. To date, 1758 trials have been completed and 1082 are actively recruiting new participants. Of these active studies, many are based in New york City."
Is the age cap for this research project 45 years and above?
"This medical trial is limited to those between the ages of 2 and 29. There are 982 studies for minors, while elder patients have access to 3312 clinical trials."
To what extent is Everolimus a secure treatment option for patients?
"The safety of Everolimus is rated a 1 because it has yet to go through the necessary trials for full efficacy and safety testing."
Is this experimental research still open for participants?
"As indicated on clinicaltrials.gov, this medical experiment has been actively seeking participants since its initial posting date of July 24th 2018 and was last modified on August 18th 2022."
Who may partake in the experiment, taking into consideration all eligibility requirements?
"Recruitment for this trial is actively seeking 15 individuals suffering from leukemia ranging in age between 2 and 29. Eligibility requirements are outlined as follows: CNS status may be accepted if other sites of malignancy exist, performance score must meet either Karnofsky or Lansky standards (depending on subject's age), patients rendered immobile due to paralysis will still qualify as ambulatory, histology confirming diagnosis at the onset or relapse, 1 year old minimum with 30 years being the upper limit. Lymphoma sufferers also eligible."
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