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R-MVST Cells for Viral Infections
Study Summary
This trial is testing a cell therapy called R-MVST for safety and feasibility in patients with refractory viral reactivation and/or symptomatic disease caused by Epstein Barr Virus (EBV), cytomegalovirus (CMV), adenovirus (ADV) or BK virus. The cell therapy will be generated on-demand from the closest partially human leukocyte antigen (HLA)-matched (minimum haploidentical) healthy donors or from the original allo-transplant donor if available.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am 18 years or older.I had a transplant and now have a virus affecting my body because standard treatments didn't work well.I have had multiple or recurring viral infections after a bone marrow transplant.I'm sorry, but that is not a complete criterion. Please provide more information about the criterion to enable me to rewrite it.
- Group 1: Group A: Allogenic Stem Cell Transplant Recipient (SCT)
- Group 2: Group B: Solid organ transplant recipients (SOT)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is it dangerous to receive Rapidly generated virus specific T (R-MVST) cells?
"Power's team has given R-MVST cells a score of 1 on a scale of 1 to 3. This is due to the fact that, as a Phase 1 trial, there is only limited data supporting both safety and efficacy."
Is this study still open to new participants?
"Unfortunately, this particular clinical trial is not recruiting patients at the moment. Although, there are many other trials (904 to be exact) that are in the process of looking for patients to enroll."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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