NR Alone for High Blood Pressure

Phase-Based Progress Estimates
UF Institute on Aging, Gainesville, FLHigh Blood PressureWalking Exercise - Behavioral
55 - 105
All Sexes
What conditions do you have?

Study Summary

This trial suggests that nicotinamide riboside may help hypertensive older adults by enhancing the effects of exercise therapy.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Baseline; Week 3; Week 6

Week 6
Arterial Stiffness
Baseline; Week 6
Change in SBP

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

NR Alone
1 of 3
NR plus Walking Exercise
1 of 3
Walking Exercise plus Placebo
1 of 3

Active Control

74 Total Participants · 3 Treatment Groups

Primary Treatment: NR Alone · No Placebo Group · Phase 1

NR Alone
ActiveComparator Group · 1 Intervention: Nicotinamide Riboside (NR) · Intervention Types: Drug
NR plus Walking ExerciseActiveComparator Group · 2 Interventions: Walking Exercise, Nicotinamide Riboside (NR) · Intervention Types: Behavioral, Drug
Walking Exercise plus Placebo
ActiveComparator Group · 1 Intervention: Walking Exercise · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline; week 3; week 6

Who is running the clinical trial?

University of FloridaLead Sponsor
1,262 Previous Clinical Trials
699,436 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,448 Previous Clinical Trials
4,279,426 Total Patients Enrolled
Robert Mankowski, PhDPrincipal InvestigatorUniversity of Florida
1 Previous Clinical Trials
40 Total Patients Enrolled

Eligibility Criteria

Age 55 - 105 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

Frequently Asked Questions

Are there any vacancies open for participants in this examination?

"Indeed, reveals that this research venture is currently recruiting subjects. Launched on July 28th 2020 and revised as recently as September 15th 2022, the trial seeks 74 volunteers from a single location." - Anonymous Online Contributor

Unverified Answer

What is the size of the cohort participating in this clinical trial?

"Affirmative. confirms that this medical experiment, initially posted on July 28th 2020 is actively looking for patients to join the study. Currently 74 participants need to be recruited from 1 clinical site." - Anonymous Online Contributor

Unverified Answer

Have any experiments been conducted to explore the possible benefits of NR Alone?

"Currently, there are 15 active studies being conducted on the effectiveness of NR Alone. One such study is in its final phase. While Winston-Salem, North Carolina houses many of these trials, 19 other sites across the USA have projects related to this treatment underway as well." - Anonymous Online Contributor

Unverified Answer

Are there significant risks associated with NR Alone?

"Due to its current status as a Phase 1 investigation, the safety of NR Alone was assigned an estimated rating of one. This reflects limited data supporting both efficacy and safety outcomes." - Anonymous Online Contributor

Unverified Answer

Does this experiment permit persons under the age of seventy to take part?

"For this medical trial, individuals aged between 55 and 105 years are eligible for enrollment." - Anonymous Online Contributor

Unverified Answer

Are there any eligibility criteria for my participation in this medical research?

"For this hypertension clinical trial, 74 individuals aged between 55 and 105 are being sought. In addition to age requirements, participants must have daytime average systolic BP of at least 130 mmHg but not exceeding 160 mmHg., be inactive with less than 150 minutes per week of moderate physical activity as reported on the CHAMPS questionnaire., consent to randomization into either treatment group and agree to complete all study procedures." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.