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mTOR inhibitor

nab-sirolimus (also known as ABI-009, nab-rapamycin, albumin-bound rapamycin) for Pulmonary Hypertension

Phase 1
Waitlist Available
Research Sponsored by Aadi Bioscience, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 16 weeks
Awards & highlights

Study Summary

This trial is testing if ABI-009 can help improve Pulmonary Hypertension.

Eligible Conditions
  • Pulmonary Hypertension

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~16 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 16 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
DLT
MTD

Trial Design

1Treatment groups
Experimental Treatment
Group I: nab-sirolimus (also known as ABI-009, nab-rapamycin, albumin-bound rapamycin)Experimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
nab-sirolimus (also known as ABI-009, nab-rapamycin, albumin-bound rapamycin)
2017
Completed Phase 1
~20

Find a Location

Who is running the clinical trial?

Aadi Bioscience, Inc.Lead Sponsor
16 Previous Clinical Trials
526 Total Patients Enrolled
Aadi, LLCLead Sponsor
7 Previous Clinical Trials
297 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many study locations are currently administering this trial?

"This trial is presently open to patients at 6 different sites, located in Torrance, Pittsburgh and Tucson as well as other cities. To ease the burden of travel, it would be best if you selected a clinic close to your home when signing up for this study."

Answered by AI

What potential risks should be taken into account when prescribing ABI-009, nab-rapamycin, albumin-bound rapamycin?

"Due to a lack of clinical data, ABI-009, nab-rapamycin and albumin bound rapamycin were assigned an initial safety rating of 1. This is because the trial currently taking place is phase one and therefore has limited efficacy and safety evidence."

Answered by AI

What is the typical purpose of consuming ABI-009, nab-rapamycin and albumin-bound rapamycin?

"ABI-009, nab-rapamycin, albumin-bound rapamycin is the go-to medication for treating organ transplantation. This pharmaceutical compound has also proven beneficial in managing liver failure, acute prophylaxis of hypovolemia and adult respiratory distress syndrome."

Answered by AI

How many individuals are participating in this trial?

"Unfortunately, this trial is not enrolling new patients at the moment. It was initially put up on April 1st 2017 and amended for the last time on August 22nd 2022. If you're still searching for studies to join, there are presently 764 trials recruiting those with hypertension; 253 involving ABI-009, nab-rapamycin or albumin-bound rapamycin that are actively accepting participants."

Answered by AI

Are applications currently being accepted for this experiment?

"The information found on clinicaltrials.gov implies that this research is not currently recruiting participants; the study was first posted in April of 2017 and most recently updated August 22, 2022. Nonetheless, there are over a thousand other medical trials actively searching for members to join their experiments."

Answered by AI
~2 spots leftby Apr 2025