Donzakimig Safety Study in Healthy Subjects
Trial Summary
Do I have to stop taking my current medications for this trial?
The trial protocol does not specify whether you need to stop taking your current medications. However, since the trial is for healthy participants, it's likely that you should not be on any significant medications. Please consult with the trial coordinator for specific guidance.
What data supports the idea that Donzakimig Safety Study in Healthy Subjects (also known as: Donzakimig, UCB-1381) is an effective drug?
The available research does not provide any specific data on the effectiveness of Donzakimig, UCB-1381. The studies mentioned focus on other drugs and treatments for conditions like osteoporosis, leukemia, and rheumatoid arthritis, but none of them discuss Donzakimig or its effectiveness for any condition.12345
What existing safety data is available for Donzakimig (UCB-1381)?
Is the drug Donzakimig a promising treatment?
What is the purpose of this trial?
The purpose of the study is to investigate the safety, tolerability, and pharmacokinetic parameters of 2 dose strengths of donzakimig, each administered subcutaneously as a single dose, in healthy Chinese and Japanese study participants.
Research Team
UCB Cares
Principal Investigator
0018445992273
Eligibility Criteria
This trial is for healthy Chinese and Japanese adults aged 18-55 with a BMI of 18 to 30kg/m2. Participants must be in good health as confirmed by medical exams, tests, and cardiac assessment. They should also have all four grandparents of the same descent (Chinese or Japanese) as themselves.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single subcutaneous dose of donzakimig or placebo
Follow-up
Participants are monitored for safety and pharmacokinetics after treatment
Treatment Details
Interventions
- Donzakimig
Find a Clinic Near You
Who Is Running the Clinical Trial?
UCB Biopharma SRL
Lead Sponsor
Jean-Christophe Tellier
UCB Biopharma SRL
Chief Executive Officer since 2015
MD from University of Reims Champagne-Ardenne, Rheumatology specialization from University of Paris V, Executive business programs at Harvard and INSEAD
Dr. Iris Loew-Friedrich
UCB Biopharma SRL
Chief Medical Officer since 2014
MD from University of Leuven, PhD in Medical Sciences from University of Leuven