Your session is about to expire
← Back to Search
Tilt Table Therapy for Parkinson's Disease with Orthostatic Hypotension
N/A
Recruiting
Research Sponsored by University of California, San Diego
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Diagnosis of idiopathic Parkinson Disease using the Movement Disorders Society (MDS) Clinical Diagnostic Criteria
Age at least 50 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 30 months
Awards & highlights
Study Summary
This trial will study how low blood pressure (BP) affects brain function in people with Parkinson's disease (PD), who often experience problems thinking and orthostatic hypotension (OH), i.e., low BP when standing.
Who is the study for?
This trial is for people over 50 with Parkinson's Disease (PD) who can walk without help and speak English fluently. They should be in the early to moderate stages of PD but not have unstable medical conditions, uncontrolled diabetes, recent fainting episodes, severe involuntary movements, significant carotid artery narrowing, hearing or vision impairments not corrected by devices, pregnancy, dementia including PD dementia, a history of stroke or brain surgery.Check my eligibility
What is being tested?
The study tests how blood pressure affects thinking and brain blood flow in PD patients when they change positions from lying down to standing up. It uses wearable technology to monitor these changes continuously during cognitive tests performed both while supine and upright.See study design
What are the potential side effects?
There are no direct side effects from the interventions being studied since it involves non-invasive monitoring using a tilt table test. However, participants may experience their usual symptoms related to orthostatic hypotension such as lightheadedness or dizziness.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have been diagnosed with Parkinson's Disease.
Select...
I am at least 50 years old.
Select...
My Parkinson's is early to moderate; I can walk without help.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 30 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 30 months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Delis-Kaplan Executive Function System Verbal Fluency Test score (number of words per minute). Minimum: 0; Maximum: N/A; higher is better
Oxygenated and deoxygenated hemoglobin change from baseline
Trial Design
2Treatment groups
Experimental Treatment
Group I: Upright cognitive testing firstExperimental Treatment1 Intervention
The cognitive testing sessions will be alternated between supine and upright positions.
This group will perform cognitive testing sessions in the following order: 1) upright, 2) supine, 3) upright, 4) supine.
Group II: Supine cognitive testing firstExperimental Treatment1 Intervention
The cognitive testing sessions will be alternated between supine and upright positions.
This group will perform cognitive testing sessions in the following order: 1) supine, 2) upright, 3) supine, 4) upright.
Find a Location
Who is running the clinical trial?
Beth Israel Deaconess Medical CenterOTHER
837 Previous Clinical Trials
13,010,212 Total Patients Enrolled
Drexel UniversityOTHER
150 Previous Clinical Trials
47,641 Total Patients Enrolled
University of California, San DiegoLead Sponsor
1,121 Previous Clinical Trials
1,520,864 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have been diagnosed with Parkinson's Disease.I have been diagnosed with dementia.I am taking medication for high blood pressure or medications that affect my blood pressure.I am at least 50 years old.My Parkinson's is early to moderate; I can walk without help.I don't have large involuntary movements or they're controlled by medication.I have fainted in the last week.I have diabetes or another disease that is not under control.I do not have any current severe or uncontrolled health issues.You have a moderate or severe narrowing in your carotid artery.I have had deep brain stimulation surgery.I have had a stroke or brain bleed in the past.
Research Study Groups:
This trial has the following groups:- Group 1: Supine cognitive testing first
- Group 2: Upright cognitive testing first
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How many participants have been enrolled in this clinical trial?
"Affirmative. According to the information collated on clinicaltrials.gov, this medical trial is recruiting participants at present time. It was first posted on December 14th 2021 and recently modified November 8th 2022. 60 individuals need to be recruited from a single location for the study's completion."
Answered by AI
Are there any vacancies for participation in this experiment?
"Affirmative. The information hosted on clinicaltrials.gov reveals that the trial, which was posted on December 14th 2021 and updated most recently in November 8th 2022, is actively seeking 60 volunteers from one medical centre."
Answered by AI
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger