← Back to Search

Grape extract for Head and Neck Cancers

Phase 1
Waitlist Available
Led By Rebecca Redman, MD
Research Sponsored by University of Louisville
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up total followup of six months
Awards & highlights

Study Summary

This trial will study whether grape powder can help reduce inflammation and mouth sores during radiation and chemotherapy for head and neck tumors.

Eligible Conditions
  • Head and Neck Cancers
  • Mouth Sore

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~total followup of six months
This trial's timeline: 3 weeks for screening, Varies for treatment, and total followup of six months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Pain caused by oral mucositis
Secondary outcome measures
Level of immune biomarkers in blood
Level of immune biomarkers in mucosal tissue

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: 1 - Grape extractExperimental Treatment1 Intervention
Grape extract self-administered daily by mouth for 35 days during chemoradiation therapy.
Group II: 2 - Lortab, Fentanyl patch, mouthwashActive Control1 Intervention
Standard oral mucositis therapy such as pain medication and anti-fungal mouth washes will be prescribed according to product labels.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Grape extract
2012
Completed Phase 1
~60

Find a Location

Who is running the clinical trial?

University of LouisvilleLead Sponsor
338 Previous Clinical Trials
75,924 Total Patients Enrolled
James Graham Brown Cancer CenterOTHER
43 Previous Clinical Trials
9,158 Total Patients Enrolled
Rebecca Redman, MDPrincipal InvestigatorJames Graham Brown Cancer Center, University of Louisville

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Biochimica et Biophysica Acta (BBA) - Reviews on CancerJournal
Extracellular Vesicles as Emerging Targets in Cancer: Recent Development from Bench to Bedside
Wu, Kerui, Fei Xing, Shih-Ying Wu, and Kounosuke Watabe. 2017. “Extracellular Vesicles as Emerging Targets in Cancer: Recent Development from Bench to Bedside”. Biochimica Et Biophysica Acta (BBA) - Reviews on Cancer. Elsevier BV. doi:10.1016/j.bbcan.2017.10.001.
clinicaltrials.govStudy
Edible Plant Exosome Ability to Prevent Oral Mucositis Associated With Chemoradiation Treatment of Head and Neck Cancer
Rebecca Redman 2012. "Edible Plant Exosome Ability to Prevent Oral Mucositis Associated With Chemoradiation Treatment of Head and Neck Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01668849.
~5 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top