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PET Scans for Brain Inflammation in Breast Cancer
Study Summary
This trial will use PET/MRI scans and an investigational radioactive drug to measure inflammation and abnormal protein in the brain before and after chemotherapy in breast cancer patients.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I haven't needed treatment for an infection in the last month.I have a blood or clotting disorder.My cancer has spread to my brain.I am 18 years old or older.I have had a brain tumor or condition that affects my thinking.My genetic test shows I'm a low-affinity binder for a specific brain scan marker.I have been diagnosed with dementia not caused by cancer.I have a long-term infection like HIV or hepatitis C.I have a chronic inflammatory or autoimmune disease.I am female.I am a woman newly diagnosed with stage II-III breast cancer and meet specific criteria.My upcoming chemotherapy will include drugs like taxane or anthracycline.
- Group 1: Women with stage 1-4 newly diagnosed breast cancer
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any adverse effects associated with [11C]PiB and 18F-labeled DPA-714 PET scans for patients?
"Based on our analysis, [11C]PiB and 18F-labeled DPA-714 PET scan have been given a rating of 1 as this is an early phase trial. At present, there is limited data available to assess the safety or efficacy of these scans."
Is recruitment for this research project still underway?
"According to the records from clinicaltrials.gov, this trial is presently open for enrollment and has been since June 1st 2023. It was last edited on 6/7/2022."
What is the maximum capacity for enrollees in this trial?
"Affirmative. According to clinicaltrials.gov, this research experiment is still looking for participants and was first posted on June 1st 2023 with its last update occurring on July 6th 2022. It requires approximately 20 individuals from one site."
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