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Antipsychotic

Risperidone for Cocaine Use Disorder

Phase 1
Waitlist Available
Led By Walter Ling, M.D.
Research Sponsored by National Institute on Drug Abuse (NIDA)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
M/F ages 21-50
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is testing if a drug called risperidone is safe to use with cocaine, and how it affects the body and mind.

Who is the study for?
This trial is for men and women aged 21-50 who are diagnosed with cocaine dependence according to DSM-IV criteria. Participants must agree to the study's terms and sign a consent form. It excludes those with seizure history, psychiatric disorders needing medication, pregnant or nursing women, alcohol or sedative dependency, acute hepatitis, or any unsafe medical conditions.Check my eligibility
What is being tested?
The study is testing the safety of risperidone in relation to cocaine use and its interaction. It aims to see how risperidone pre-treatment changes the way people feel (subjective) and their body responds (physiological effects) when they take cocaine.See study design
What are the potential side effects?
Possible side effects of risperidone may include drowsiness, weight gain, dizziness upon standing up quickly, restlessness or an urge to move around (akathisia), muscle stiffness or tremors.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 21 and 50 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Characterization of study population
Clinical physiological response to cocaine challen
Degree of drug craving
+7 more

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Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)Lead Sponsor
2,461 Previous Clinical Trials
2,617,014 Total Patients Enrolled
Walter Ling, M.D.Principal InvestigatorFriends Research Institute, Inc.
38 Previous Clinical Trials
4,105 Total Patients Enrolled

Media Library

Risperidone (Antipsychotic) Clinical Trial Eligibility Overview. Trial Name: NCT00000339 — Phase 1
Cocaine Use Disorder Research Study Groups:
Cocaine Use Disorder Clinical Trial 2023: Risperidone Highlights & Side Effects. Trial Name: NCT00000339 — Phase 1
Risperidone (Antipsychotic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00000339 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research experiment permit individuals aged 75 or younger to participate?

"This clinical trial is enrolling individuals between the ages of 21 and 50."

Answered by AI

Am I eligible to be a participant in this investigation?

"This medical experiment is only enrolling individuals aged 21-50 who have been diagnosed with cocaine dependency and meet the DSM-IV criteria. A total of 13 subjects will be admitted, provided they agree to the study's conditions and sign an informed consent form."

Answered by AI

Are there any current vacancies in this clinical trial?

"According to clinicaltrials.gov, this trial is not currently recruiting participants. It was first listed on June 1st 1996 and last updated January 10th 2017; however, there are 18 other medical experiments that are still seeking volunteers in the present day."

Answered by AI

To what extent does this treatment pose a threat to human health?

"The safety of this treatment is rated a 1 due to the fact that it's only in Phase 1 trials, so there are scanty data points verifying its efficacy and security."

Answered by AI

Who else is applying?

What site did they apply to?
Friends Research Institute
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Infusion Laboratory: Protocol 3 (Risperidone) - 4
1996. "Infusion Laboratory: Protocol 3 (Risperidone) - 4". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00000339.
~0 spots leftby Apr 2025
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