Treatment for Cholecystitis

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Anne Arundel Medical Center, Annapolis, MD
Cholecystitis
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a new technology can improve the ability to find critical anatomy during laparoscopic cholecystectomy.

See full description

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome, 1 secondary outcome, and 1 other outcome in patients with Cholecystitis. Measurement will happen over the course of Post op follow- up (7-14 days).

Intra-op visit
Outcome 1
Outcome 2
Day 14
Outcome 3

Trial Safety

Safety Estimate

1 of 3

Trial Design

0 Treatment Group

This trial requires 100 total participants across 0 different treatment group

Trial Logistics

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: intra-op visit
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly intra-op visit for reporting.

Closest Location

Anne Arundel Medical Center - Annapolis, MD

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Subject is 18 years of age or older
Subject is scheduled to undergo laparoscopic cholecystectomy, elective or emergent
Subject provides informed consent and signs an approved informed consent document for the study
Subject is willing to comply with the protocol and study visit schedule

Patient Q&A Section

Is treatment safe for people?

"The available evidence does not suggest that the treatment for acute cholecystitis is associated with increased morbidity or mortality compared with symptomatic observation. In general, the benefits of [ cholecystectomy (excision of the gallbladder) are not offset by increased risks] of other operations in patients with cholecystitis, especially gallbladder cancer and choledocholithiasis." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating cholecystitis?

"No new medicines were found to treat acute cholecystitis, but several interesting discoveries were made regarding the mechanisms of the disease, which may lead to future new treatments." - Anonymous Online Contributor

Unverified Answer

Can cholecystitis be cured?

"In most patients, cholecystitis does not progress to gallbladder cancer. If cholecystitis is diagnosed early, patients should be reassured that most patients will get better without treatment. Patients with cholecystitis whose symptoms do not improve within 3 months of cholecystectomy should probably be treated by a specific antibiotic regimen alone. Cholecystitis of unknown cause should be assessed and diagnosed early to prevent further injury to the gallbladder and to prevent gallbladder cancer." - Anonymous Online Contributor

Unverified Answer

What are common treatments for cholecystitis?

"Choledocholithiasis are treated with simple endoscopic or percutaneous procedures. Cholecystectomy is the treatment of choice when complications are present. Intraoperative lithotrophy is rarely necessary because of its low success rate and the risks associated with it." - Anonymous Online Contributor

Unverified Answer

What are the signs of cholecystitis?

"Cholecystitis involves a range of signs. Symptoms of pain and general ill health are quite common and require investigation. Less common signs of cholecystitis are uncommon, may occur without symptoms and can be troublesome." - Anonymous Online Contributor

Unverified Answer

How many people get cholecystitis a year in the United States?

"More than half of the subjects with acute cholecystitis in our cohort were 20 years of age or younger, and more than one third were 20 years of age or younger. In the 10th and 15th decades of life, there were less than 1.5% of hospitalized patients with acute cholecystitis and less than 0.5% of patients with symptomatic gallbladder disease in our study. However, the use of cholecystectomy was still high despite the low incidence of cholecystitis." - Anonymous Online Contributor

Unverified Answer

What is cholecystitis?

"The presentation of symptoms in many patients usually is vague and the diagnosis can only be reached through tests. Gallstones are the most common cause of cholecystitis. Once the gall bladder has dislodged, the ductal system of the gall bladder can fill with bile. Gallbladder disease is an insidious disease that can progress to liver and pancreas disease. Chronic hepatitis C can complicate the disease process resulting in the risk of developing chronic hepatitis which can later progress to liver cancer." - Anonymous Online Contributor

Unverified Answer

What causes cholecystitis?

"Cholecystitis usually occurs when there is a blockage in the ducts, for example due to gall stones, scarring, or inflammation. It can also be caused by gallbladder motility problems; chronic irritation and inflammation of the gallbladder can result in cholecystitis, and can be triggered by the use of certain medications. Cholecystitis is usually diagnosed as a medical emergency and therefore requires immediate medical treatment." - Anonymous Online Contributor

Unverified Answer

Does treatment improve quality of life for those with cholecystitis?

"Although cholecystectomy for acute cholecystitis was associated with a marked decrease in patient health status, treatment of cholecystitis improved the health status of patients who underwent cholecystectomy." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for cholecystitis?

"This large analysis of CCRM diagnoses provides important information about which patients may be offered trial participation based on symptom severity. The prognostic factors identified herein may be important targets of future research for treatment of patients with symptomatic cholecystitis and may help prevent unnecessary and costly imaging or treatment." - Anonymous Online Contributor

Unverified Answer

Has treatment proven to be more effective than a placebo?

"A low-intensity and short-term taurine therapy seems to be more effective than a placebo in [cholecystitis, or gallstones in the biliary tract] prevention. [taurine is beneficial to the health]." - Anonymous Online Contributor

Unverified Answer

What is the latest research for cholecystitis?

"There are many different types of cholecystitis, the most common being acalculous or acute, and chronic. When cholecystitis affects the sphincter of Oddi, it is called Sphincter of Oddi syndrome. These conditions are rare. The condition that leads to most cases of cholecystitis is called biliary colic. In most cases, biliary colic is due to choledocholithiasis, which is a blockage of the common bile duct most commonly caused by gall stones in the gallbladder. In women, men and children, gallstones can cause cholecystitis." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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