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Genetic Testing for Digestive System Tumors

Phase 1
Waitlist Available
Led By Niloy J Samadder
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 3 months
Awards & highlights

Study Summary

This trial is investigating whether changes in genes are common in people with solid tumors. The results may help doctors better understand and treat people with genetic mutations.

Eligible Conditions
  • Digestive System Tumors
  • Head and Neck Cancers
  • Cancer
  • Genitourinary Cancers
  • Cancer of the Female Reproductive System
  • Musculoskeletal Tumor
  • Skin Cancer
  • Breast Cancer
  • Brain Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Difference between prevalence of positive pathogenic germline mutations
Incidence rate of germline pathogenic genetic mutations in cancer patients seen at St Vincent's and uptake rate of cascade testing in families
Prevalence of pathogenic germline mutations
+1 more
Secondary outcome measures
Differences in survey responses between patient groups

Trial Design

1Treatment groups
Experimental Treatment
Group I: Prevention (pre-genetic test counseling, genetic testing)Experimental Treatment4 Interventions
Patients watch a pre-recorded genetic counseling video and those who consent to genetic testing undergo collection of blood samples. Patients also complete surveys over 5-15 minutes each prior to receiving their genetic test results and following the receipt of genetic test results.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Biospecimen Collection
2004
Completed Phase 2
~1920

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,613 Previous Clinical Trials
40,918,085 Total Patients Enrolled
Mayo ClinicLead Sponsor
3,177 Previous Clinical Trials
3,758,121 Total Patients Enrolled
Niloy J SamadderPrincipal InvestigatorMayo Clinic
5 Previous Clinical Trials
2,835 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research project still recruiting participants?

"Clinicaltrials.gov showcases that this medical trial is not currently seeking patients despite having initially been posted on June 30th 2020 and last updated February 17th 2022. Nevertheless, there are still 7425 other clinical studies actively recruiting participants at the present time."

Answered by AI

What risks should one be cognizant of when considering genetic testing?

"Our experts at Power have judged the safety of Genetic Testing to be a 1, as this is still an early Phase 1 trial and there has been limited data collected on its efficacy or risks."

Answered by AI
~48 spots leftby Mar 2025