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OPC for Breast Cancer

Phase 1
Waitlist Available
Led By Antonio Giordano, MD
Research Sponsored by Medical University of South Carolina
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 85 days
Awards & highlights

Study Summary

This trial will test the effects of a new drug, OPC, on AGE levels in patients with metastatic breast cancer.

Eligible Conditions
  • Breast Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~85 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 85 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
AGE level reduction
Secondary outcome measures
Correlation between AGE level and A1C
Correlation between AGE level and c-reactive protein (CRP)
Correlation between AGE level and changes to BMI
+11 more

Side effects data

From 2011 Phase 1 trial • 6 Patients • NCT02169427
33%
Somnolence
17%
Headache
17%
Wound
17%
Frequent Bowel Movements
100%
80%
60%
40%
20%
0%
Study treatment Arm
Opicapone (OPC)

Trial Design

1Treatment groups
Experimental Treatment
Group I: OPCExperimental Treatment1 Intervention
During weeks 1- 12, subjects will take one OPC tablet in the morning and in the evening, about 12 hours apart.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
OPC
2011
Completed Phase 1
~10

Find a Location

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor
933 Previous Clinical Trials
7,394,626 Total Patients Enrolled
10 Trials studying Breast Cancer
640 Patients Enrolled for Breast Cancer
Antonio Giordano, MDPrincipal InvestigatorMedical University of South Carolina
2 Previous Clinical Trials
404 Total Patients Enrolled
Michael Lilly, MDPrincipal InvestigatorMedical University of South Carolina
9 Previous Clinical Trials
205 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
AGE Levels in ER+ Metastatic Breast Cancer Patients Receiving Endocrine Therapy
2017. "AGE Levels in ER+ Metastatic Breast Cancer Patients Receiving Endocrine Therapy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03092635.
~1 spots leftby Apr 2025
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