← Back to Search

Alkylating agents

filgrastim for Breast Cancer

Phase 1
Waitlist Available
Research Sponsored by City of Hope Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to death
Awards & highlights

Study Summary

This trial is studying how well combination chemotherapy, amifostine, and peripheral stem cell transplantation works in treating patients with breast cancer.

Eligible Conditions
  • Breast Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to death
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to death for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility of high dose chemotherapy in advance breast cancer patients.

Trial Design

1Treatment groups
Experimental Treatment
Group I: High Dose chemotherapy followed by cell rescueExperimental Treatment6 Interventions
Doxorubicin, cyclophosphamide, Taxol, amifostine
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
amifostine trihydrate
2005
Completed Phase 3
~1190
filgrastim
1997
Completed Phase 3
~7260
cyclophosphamide
1994
Completed Phase 3
~8140
doxorubicin hydrochloride
1994
Completed Phase 3
~9590
paclitaxel
1996
Completed Phase 3
~4310
peripheral blood stem cell transplantation
1997
Completed Phase 3
~4330

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,658 Previous Clinical Trials
40,924,474 Total Patients Enrolled
939 Trials studying Breast Cancer
1,543,345 Patients Enrolled for Breast Cancer
City of Hope Medical CenterLead Sponsor
565 Previous Clinical Trials
1,921,445 Total Patients Enrolled
42 Trials studying Breast Cancer
6,634 Patients Enrolled for Breast Cancer
George Somlo, MDStudy ChairCity of Hope Comprehensive Cancer Center
10 Previous Clinical Trials
534 Total Patients Enrolled
6 Trials studying Breast Cancer
411 Patients Enrolled for Breast Cancer

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals over the age of sixty eligible to participate in this clinical trial?

"According to the stated restrictions, individuals must be between 18-59 years of age in order to qualify for this medical trial."

Answered by AI

Has filgrastim received authorization from the FDA?

"As this is only a Phase 1 trial, which lacks evidence of safety and efficacy according to our team at Power, filgrastim received the lowest score possible-1."

Answered by AI

Is this experiment novel or has it been conducted before?

"Since its initial study in 1997, sponsored by Alfacell and involving 300 participants, filgrastim has enjoyed a remarkable amount of research. Presently there are 1759 active studies conducted across 3488 cities and 82 countries concerning this medication's efficacy. Following the first trial in '97, it was granted Phase 3 drug approval."

Answered by AI

Are there still opportunities to participate in this research?

"Per the clinicaltrials.gov website, this particular medical trial is no longer in need of participants; its initial posting was on May 18th 1999 and it's been updated as recently as February 17th 2022. Despite that, there are still 4359 other trials actively recruiting at this time."

Answered by AI

To whom is enrollment in this study available?

"This medical trial is searching for 15 individuals with breast cancer, aged 18 to 59 years-old. It is essential that they meet the following criteria: Disease Characteristics - histologically verified instance of Stage IV metastatic cancer responding well to prior chemotherapy or high risk primary disease; Patient Characteristics - between eighteen and fifty nine, Karnofsky Performance Status 80%-100%; Life expectancy not specified; Hematopoietic/Hepatic/Renal parameters as noted in above text; Cardiovascular no prior valvular heart illness or arrhythmia; Pulmonary conditions according to given information. Additionally, applicants must have completed"

Answered by AI

What medical conditions typically reap the benefits of filgrastim?

"filgrastim is frequently utilized for the management of leukemia, but can also be efficacious in treating metastatic bladder cancer and non-small cell lung cancers."

Answered by AI

What is the current sample size for this research endeavor?

"This research trial is not currently accepting patients. Initially posted on May 18th, 1999 and last modified February 17th 2022, it cannot be used to join a study at this time. Alternatives can be found through 2600 studies that admit participants with breast cancer or the 1759 trials actively recruiting for filgrastim treatments."

Answered by AI
~1 spots leftby Apr 2025