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spartalizumab for Breast Cancer
Study Summary
This trial is a Phase Ib, open label, dose escalation study of spartalizumab + LAG525 in combination with NIR178, capmatinib, MCS110, or canakinumab, followed by a dose expansion in adult patients with advanced or metastatic TNBC.
- Breast Cancer
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Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Frequently Asked Questions
Has the FDA certified spartalizumab for public use?
"Spartalizumab's safety ranking on a scale of 1 to 3 is 1, due to it being in Phase I trials and the lack of data supporting its efficacy."
Would this research be considered pioneering in its field?
"Research into spartalizumab began in 2011 with an initial trial sponsored by Novartis Pharmaceuticals. This first study had 185 participants, and it led to the drug's Phase 1 approval. There are currently 52 active studies for spartalizumab spread across 352 cities and 54 countries."
What is the maximum capacity of participants for this medical research?
"Unfortunately, this trial is not accepting any new patients at present. Initially posted on January 31st 2019, the study has been recently modified as of November 18th 2022. At the moment there are 2351 trials for breast cancer and 52 studies using spartalizumab that are actively enrolling participants if you wish to explore other options."
What has spartalizumab been demonstrated to be beneficial for?
"Spartalizumab is most commonly prescribed to treat neonatal-onset multisystem inflammatory disease (nomid). Additionally, it can be utilized for familial cold autoinflammatory syndrome (fcas), muckle-wells syndrome (mws), and active systemic juvenile idiopathic arthritis."
Is recruitment for this trial still open to participants?
"As found on clinicaltrials.gov, the trial is not presently looking for participants. First posted in January of 2019 and last updated November 18th 2022, there are no more recruitment efforts taking place at this time; however, 2403 other studies are still enrolling patients."
Can you summarize the results of prior experiments pertaining to spartalizumab?
"Currently, there are 52 studies being conducted on spartalizumab. Out of those trials, 7 have reached Phase 3 and further 1364 medical centres across the country are participating in this research. Notably, many of these sites are located within New york City itself."
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