Study Summary
This trial will test a new device for repairing a torn ACL. 10 patients will use the new device, and 10 will have standard ACL surgery.
- Anterior Cruciate Ligament Injury
- Anterior Cruciate Ligament Tear
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 5 Secondary · Reporting Duration: At 3-months post-op
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Standard ACL reconstruction
1 of 2
ACL repair with MIACH scaffold
1 of 2
Active Control
Experimental Treatment
20 Total Participants · 2 Treatment Groups
Primary Treatment: ACL Repair with MIACH Scaffold · No Placebo Group · Phase 1
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 65 · All Participants · 3 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:About The Reviewer
Michael Gill - B. Sc.
First Published: October 5th, 2021
Last Reviewed: November 22nd, 2022
Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.
- Kiapour, Ata M., Kirsten Ecklund, Martha M. Murray, Brett Flutie, Christina Freiberger, Rachael Henderson, Dennis Kramer, et al.. 2019. “Changes in Cross-sectional Area and Signal Intensity of Healing Anterior Cruciate Ligaments and Grafts in the First 2 Years After Surgery”. The American Journal of Sports Medicine. SAGE Publications. doi:10.1177/0363546519850572.
- Murray, Martha M., Brett M. Flutie, Leslie A. Kalish, Kirsten Ecklund, Braden C. Fleming, Benedikt L. Proffen, and Lyle J. Micheli. 2016. “The Bridge-enhanced Anterior Cruciate Ligament Repair (BEAR) Procedure”. Orthopaedic Journal of Sports Medicine. SAGE Publications. doi:10.1177/2325967116672176.
- Barnett, Samuel C., Martha M. Murray, Sean W. Flannery, Danilo Menghini, Braden C. Fleming, Ata M. Kiapour, Benedikt Proffen, et al.. 2021. “ACL Size, but Not Signal Intensity, Is Influenced by Sex, Body Size, and Knee Anatomy”. Orthopaedic Journal of Sports Medicine. SAGE Publications. doi:10.1177/23259671211063836.
- 2015. "Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02292004.