Your session is about to expire
← Back to Search
Puberty Blockers for Gender Dysphoria
Study Summary
This trial will examine the effects of puberty blockers on bone marrow composition in transgender youth.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I am between 9-14 years old if AMAB, or 9-13 if AFAB.I am a patient at the Boston or Cincinnati Children's Hospital Transgender Clinic starting puberty blockers.I have a chronic condition like cystic fibrosis that affects bone health.I haven't taken drugs affecting bone health in the last 3 months.You have metal in your body that would prevent you from having an MRI.You have a condition that makes you unable to do an MRI, like a developmental disorder or claustrophobia.My match for the study will be similar in age, race/ethnicity, sex at birth, and body weight.My body is in the early to middle stages of puberty.I am a patient at the BCH or CCHMC Transgender Clinic and started puberty blockers within the last six weeks.
- Group 1: Transgender Participant
- Group 2: Cisgender Control Participant
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this experiment open to adults who have reached the legal age of majority?
"The age range for participants in this study is between 9 and 14 years old."
How many participants are being recruited for this clinical research?
"Affirmative, information on clinicaltrials.gov declares that this medical experiment is actively enrolling participants. It was first posted in September 15th 2020 and most recently updated on the 8th of September 2022. The study requires 80 volunteers from two separate locations."
What aims is this exploration trying to accomplish?
"The primary objective of this research project, which will be monitored for a period extending from the Baseline to 12 months, is assessing bone marrow adiposity through MRI. The secondary outcomes include measuring Lumbar spine BMD Z-score using DXA and Hip bone mineral density (g/cm2) as well as Volumetric bone mineral density (vBMD) via pQCT scans acquired at 3%, 38%, and 66% of tibial length proximal to the distal growth plate."
Could individuals still enroll in this clinical experiment?
"This clinical trial, initially published on September 15th 2020, is actively seeking participants. Data hosted on clinicaltrials.gov was last updated on September 8th 2022."
What criteria must individuals fulfill to be eligible for this medical research?
"This trial is seeking 80 participants aged between 9 and 14 who are currently undergoing puberty. Eligible candidates must have visited either the BCH Transgender Clinic or CCHMC Transgender Clinic, be within 6 weeks of initiation pubertal blockade treatment (i.e., using drugs such as Lupron or Vantas), willingly give informed consent/assent (with parent/guardian permission necessary if applicable) , display a Tanner Stage II/III, fit into the age bracket associated with their assigned gender at birth (AMAB: 9-14 years old; AFAB: 9-13 years old), match controls in terms of race/"
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How responsive is this trial?
Typically responds via
Most responsive sites:
- Cincinnati Children's Hospital Medical Center: < 48 hours
Average response time
- < 2 Days
Share this study with friends
Copy Link
Messenger