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Lobeline Safety for Methamphetamine Addiction

Phase 1

Waitlist Available

Led By Reese Jones, M.D.

Research Sponsored by National Institute on Drug Abuse (NIDA)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between the ages of 18 and 45 years of age

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Study Summary

This trial will test if there are any cardiovascular risks when taking Lobeline, a substance similar to methamphetamine, through the vein.

Who is the study for?

This trial is for healthy adults aged 18-45 with a history of methamphetamine use but not dependence. Participants must have used methamphetamine at least four times in their life and within the past three months without adverse effects, have a BMI between 18-30, and test negative for various drugs including amphetamines.Check my eligibility

What is being tested?

The study aims to find out if there are any significant heart-related or other health interactions when sublingual lobeline is taken together with intravenous methamphetamine.See study design

What are the potential side effects?

While specific side effects are not listed, potential risks may include cardiovascular issues due to the interaction between lobeline and methamphetamine. Other general side effects could arise from either substance individually.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 45 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Cardiovascular responses

Secondary outcome measures

Subjective effects

0 / 1Eligibility criteria met

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)Lead Sponsor

2,465 Previous Clinical Trials

2,618,623 Total Patients Enrolled

1 Trials studying Methamphetamine Addiction

8 Patients Enrolled for Methamphetamine Addiction

Reese Jones, M.D.Principal InvestigatorLangley Porter Psychiatric Institute

4 Previous Clinical Trials

66 Total Patients Enrolled

Media Library

Intravenous Methamphetamine (Other) Clinical Trial Eligibility Overview. Trial Name: NCT00439504 — Phase 1

Methamphetamine Addiction Research Study Groups:

Methamphetamine Addiction Clinical Trial 2023: Intravenous Methamphetamine Highlights & Side Effects. Trial Name: NCT00439504 — Phase 1

Intravenous Methamphetamine (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00439504 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any age restrictions for enrolment in this clinical research?

"This clinical trial has an age-range requirement for participation, with a lower threshold of 18 years and upper limit of 45."

Answered by AI

Has this therapeutic option been given a green light by the FDA?

"Considering that this is an early stage trial, our team at Power has judged its safety to be 1 on a scale of 3 due to the lack of data concerning efficacy and safety."

Answered by AI

May I be eligible to join this clinical exploration?

"To be eligible for the trial, individuals must meet two criteria: they must have a dependence on methamphetamine and should fall in between 18-45 years old. The study aims to recruit around 10 people."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Ph1 Lobeline Interaction Study - 1

2024. "Ph1 Lobeline Interaction Study - 1". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00439504.

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