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Antibiotic Irrigation for Intracranial Disease

Phase 1

Waitlist Available

Research Sponsored by Carl Snyderman

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

Study Summary

This trial will test whether using antibiotics can prevent infection when packing is placed in the nose following surgery.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Can prophylactic topical antibiotics alter the bacterial load of nasal packing following endoscopic skull base surgery

Can prophylactic topical antibiotics alter the colonization of nasal packing following endoscopic skull base surgery

Which bacteria colonize nasal packing following endoscopic skull base surgery

Secondary outcome measures

Does endoscopic skull base surgery later the nasal flora

Other outcome measures

Does nasal packing colonization correlate with causative organisms

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Drug: Antibiotic Irrigation, and Procedure/Surgery: Nasal PackingExperimental Treatment1 Intervention

Experimental group will receive nasal packing with antibiotic irrigation.

Group II: Procedure/Surgery: Nasal PackingActive Control1 Intervention

Patients will be assigned to the control group to collect data on common nasal packing colonization and appropriate antibiotic selection for the experimental group.

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Who is running the clinical trial?

Carl SnydermanLead Sponsor

1 Previous Clinical Trials

30 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What risk factors does Antibiotic Irrigation pose to individuals?

"Considering the fact that this is still a Phase 1 trial with limited safety and efficacy data, Antibiotic Irrigation has been rated at a score of 1."

Answered by AI

Are opportunities still available for participants in this experiment?

"According to the data posted on clinicialtrials.gov, this medical trial is not presently enrolling participants. The study was initially listed in December of 2022 and last edited August of that same year; however, there are two other trials currently recruiting patients."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Topical Antibiotic Prophylaxis for Nasal Packing Post-ESBS

Carl Snyderman 2023. "Topical Antibiotic Prophylaxis for Nasal Packing Post-ESBS". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04946435.