Effects of commonly used medications on mood and medication preference for Healthy Subjects

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Healthy SubjectsEffects of commonly used medications on mood and medication preference - Drug
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

This trial will study how drugs that are commonly taken for other reasons may affect mood and what drugs people prefer.

Treatment Effectiveness

Effectiveness Progress

1 of 3

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Blinded drug dose conditions

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Completed by the participant up to 4 hours after capsule ingestion.

Hour 4
Participant subjective ratings of drug value
Hour 4
Participant subjective ratings of drug liking (peak change)

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
Methamphetamine
1
Phenelzine
1
Blinded drug dose conditions

Trial Design

2 Treatment Groups

Within-Subjects Dose Conditions
1 of 2
Additional Within-Subjects Dose Conditions
1 of 2

Experimental Treatment

36 Total Participants · 2 Treatment Groups

Primary Treatment: Effects of commonly used medications on mood and medication preference · No Placebo Group · Phase 1

Within-Subjects Dose Conditions
Drug
Experimental Group · 1 Intervention: Effects of commonly used medications on mood and medication preference · Intervention Types: Drug
Additional Within-Subjects Dose Conditions
Drug
Experimental Group · 1 Intervention: Effects of commonly used medications on mood and medication preference · Intervention Types: Drug

Trial Logistics

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: completed by the participant up to 4 hours after capsule ingestion.

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,076 Previous Clinical Trials
31,020,157 Total Patients Enrolled
National Institute on Drug Abuse (NIDA)NIH
2,248 Previous Clinical Trials
2,029,045 Total Patients Enrolled
Roland R Griffiths, Ph.D.Principal InvestigatorJohns Hopkins University
7 Previous Clinical Trials
295 Total Patients Enrolled
Dustin C Lee, Ph.D.Principal InvestigatorJohns Hopkins University

Eligibility Criteria

Age 18 - 65 · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are a female age 18-65 years old.
You are fluent in written and spoken English and are capable of understanding and complying with the protocol.
You are medically healthy.
You are a non-smoker.\n
You have a history of appropriate dietary/over-the-counter/prescription/illicit drug use.
You have a body mass index between 18.5 and 35.
Appropriate use of birth control in females.

Who else is applying?

What state do they live in?
Maryland100.0%
How old are they?
18 - 65100.0%
What site did they apply to?
Behavioral Pharmacology Research Unit, Johns Hopkins Bayview Medical Center100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%
Why did patients apply to this trial?
  • "I've tried other drugs & nothing works. Hoping to do this study. Thank U"
How many prior treatments have patients received?
0100.0%

How responsive is this trial?

Typically responds via
Email100.0%
Most responsive sites:
  1. Behavioral Pharmacology Research Unit, Johns Hopkins Bayview Medical Center: < 24 hours
Average response time
  • < 2 Days
References

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