Study Summary
This trial is testing a new longer-acting local anesthetic to see if it is more effective than the standard in managing pain after surgery that involves opening the sternum.
Eligible Conditions
- Sternotomy
- Pain Management
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 3 Secondary · Reporting Duration: 72 hours post-surgery
30 days post operative
Delirium
Time to extubation in minutes will be retrieved via the electronic medical record
4-6 weeks postoperative visit
Presence of sternal wound infection
72 hours post-surgery
Morphine
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Bupivacaine
1 of 2
Liposomal bupivacaine
1 of 2
Active Control
80 Total Participants · 2 Treatment Groups
Primary Treatment: Bupivacaine · No Placebo Group · Phase 1
Bupivacaine
Drug
ActiveComparator Group · 1 Intervention: Bupivacaine · Intervention Types: DrugLiposomal bupivacaine
Drug
ActiveComparator Group · 1 Intervention: Exparel · Intervention Types: DrugTrial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 72 hours post-surgery
Who is running the clinical trial?
University of Kansas Medical CenterLead Sponsor
401 Previous Clinical Trials
158,289 Total Patients Enrolled
Jared Staab, DOPrincipal Investigator - University of Kansas Medical Center
University of Kansas Medical Center
Eligibility Criteria
Age 18+ · All Participants · 1 Total Inclusion Criteria
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Conditions
Cancer Related
Treatments