Bupivacaine for Sternotomy

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Sternotomy+1 MoreBupivacaine - Drug
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This trial is testing a new longer-acting local anesthetic to see if it is more effective than the standard in managing pain after surgery that involves opening the sternum.

Eligible Conditions
  • Sternotomy
  • Pain Management

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: 72 hours post-surgery

30 days post operative
Delirium
Time to extubation in minutes will be retrieved via the electronic medical record
4-6 weeks postoperative visit
Presence of sternal wound infection
72 hours post-surgery
Morphine

Trial Safety

Trial Design

2 Treatment Groups

Bupivacaine
1 of 2
Liposomal bupivacaine
1 of 2

Active Control

80 Total Participants · 2 Treatment Groups

Primary Treatment: Bupivacaine · No Placebo Group · Phase 1

Bupivacaine
Drug
ActiveComparator Group · 1 Intervention: Bupivacaine · Intervention Types: Drug
Liposomal bupivacaine
Drug
ActiveComparator Group · 1 Intervention: Exparel · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 72 hours post-surgery

Who is running the clinical trial?

University of Kansas Medical CenterLead Sponsor
401 Previous Clinical Trials
158,289 Total Patients Enrolled
Jared Staab, DOPrincipal Investigator - University of Kansas Medical Center
University of Kansas Medical Center

Eligibility Criteria

Age 18+ · All Participants · 1 Total Inclusion Criteria

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