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DISC-0974 for Healthy Subjects

Phase 1
Waitlist Available
Research Sponsored by Disc Medicine, Inc
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 71 days of testing
Awards & highlights

Study Summary

This study is evaluating whether a drug called DISC-0974 is safe and well tolerated in healthy volunteers.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 71 days of testing
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 71 days of testing for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Incidence of abnormal laboratory test results
Incidence of adverse events
Incidence of treatment-emergent clinically abnormal electrocardiogram (ECG)
+1 more
Secondary outcome measures
Area under the concentration-time curve (AUC)
Plasma half-life (T½)
Plasma maximum measured drug concentration (Cmax)
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Healthy Volunteer: Single Ascending Dose of PlaceboExperimental Treatment1 Intervention
Single Intravenous (IV) or Subcutaneous (SC) ascending dose in healthy volunteers
Group II: Healthy Volunteer: Single Ascending Dose of DISC-0974Experimental Treatment1 Intervention
Single Intravenous (IV) or Subcutaneous (SC) ascending dose in healthy volunteers
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
DISC-0974
2021
Completed Phase 1
~50
Placebo
1995
Completed Phase 3
~2670

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Disc Medicine, IncLead Sponsor
5 Previous Clinical Trials
427 Total Patients Enrolled
William Savage, MD, PhDStudy DirectorDisc Medicine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Study to Evaluate the Safety, Tolerability, PK and PD of DISC-0974 in Healthy Subjects
2021. "Study to Evaluate the Safety, Tolerability, PK and PD of DISC-0974 in Healthy Subjects". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04999527.
~11 spots leftby Apr 2025
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