This trial is evaluating whether Cannabidiol will improve 3 primary outcomes and 2 secondary outcomes in patients with Healthy Subjects (HS). Measurement will happen over the course of Study Visit 1 Day.
This trial requires 24 total participants across 4 different treatment groups
This trial involves 4 different treatments. Cannabidiol is the primary treatment being studied. Participants will be divided into 4 treatment groups. There is no placebo group. The treatments being tested are in Phase 1 and are in the first stage of evaluation with people.
Participation is compensated
You will be compensated for participating in this trial.
"The present double-blind study suggests that cannabidiol does not improve physical component of QOL or the overall mental/sociological well-being of volunteers with healthy subjects. This is the preliminary report to the literature." - Anonymous Online Contributor
"A combination of the presence of a family history of heart disease and BMI of above 30, or a waist circumference greater than 102 cm is most significant in identifying the healthy subjects (hs)." - Anonymous Online Contributor
"Each year, 4.9 million US adults are diagnosed with chronic disease. These include a mean of 62.0 years old men and women, or almost 16% of US adults over 65 years of age. A majority of these individuals (69.6%) have chronic disease." - Anonymous Online Contributor
"Healthy subjects often undergo a variety of health screening and related medical procedures. The prevalence and use of such preventive and diagnostic procedures are increasing in a large and varied variety of medical specialties, underscoring the important contribution that medical care plays to population mental health. It is important that the patient-doctor relationship and the practice patterns in these settings be described." - Anonymous Online Contributor
"Healthy subjects (hs) are individuals of a population where the risk or development of disease has not yet occurred. Therefore, a definition that specifies a population where a cohort of people have been screened does not meet the concept of healthy." - Anonymous Online Contributor
"In children, age and sex had the strongest effects. In adults, however, age and race also had significant effects. hs of the same sex displayed a much larger range of adiposity than hs of dissimilar sex, but both sexes displayed a much larger range of adiposity than hs." - Anonymous Online Contributor
"Laser irradiation of the irradiated area of the oral cavity is well tolerated in hs. The laser at irradiated areas has the ability to increase the number of viable lymphocytes and reduces the percentage of T-cells. The laser irradiation can possibly increase the number of CD4(+) /CD8(+) T subgroups, and decrease the percentage of CD20(+) B cells in oral cavity of hs. Hs who are irradiated on the oral cavity can be cured of bacterial gingivitis/periodontitis without the need for further therapy and long-term antibiotics application." - Anonymous Online Contributor
"New medical advances have been made in recent years, but progress has been modest. However, studies are needed to demonstrate whether new discoveries, if any, would benefit hs. Because most evidence in medical research was done using hs, current research can be very helpful for identifying promising study designs to test in hs." - Anonymous Online Contributor
"CBD can be found in all [legal] edible hemp products and in several [commonly cultivated] ornamental plants. The CBD content of these plants is widely variable. This variation underscores the need for new standardization of CBD extraction from food plants. The CBD content in food plants can be quantified using a variety of different analytical approaches. Moreover, the composition of food oil, which is an important factor in CBD intake, can be investigated using (gas) chromatography-mass spectrometry. The development of such standardized CBD analysis procedures will enhance the utilization of CBD in food/drug products and help ensure the safety of consumption." - Anonymous Online Contributor
"The addition of cannabidiol to a low-glycemic diet in obese hs subjects significantly reduced body weight and waist circumference as well as other metabolic profile variables. The cannabinoid receptor 2-selective receptor agonists is being developed with the aim of producing better anti-obesity and anti-diabetic properties compared with cannabidiol. Cannabinoid receptor agonists such as rimonabant have the ability to treat metabolic and cardiovascular disease, but there has been concern about their safety and other side effects in humans, leading to a temporary halt to development and testing. Cannabinoid receptor agonists are now undergoing evaluation in clinical trials." - Anonymous Online Contributor
"CBD has several common adverse effects in healthy subjects, and the side effects reported differ from those of placebo. Most common are dry mouth, insomnia, increased appetite, nausea, and dizziness." - Anonymous Online Contributor
"Patients with chronic disease, and patients who are not well enough to undergo the required study treatment are most likely to need hs for their hs. In most medical trials, hs are excluded because of their lack of relevance for the test. Patients, patients' relatives, and hs are the groups most likely to be affected by the study treatment." - Anonymous Online Contributor