CLINICAL TRIAL

DOT mobile app for Hiv

Waitlist Available · 18 - 65 · Male · Cambridge, MA

This study is evaluating whether a mobile health intervention can help improve adherence to the daily PrEP pill among culturally-diverse young adult men who have sex with men.

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About the trial for Hiv

Treatment Groups

This trial involves 2 different treatments. DOT Mobile App is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
DOT mobile app
OTHER
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.

Eligibility

This trial is for male patients between 18 and 65 years old. There are 2 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
We are looking for men who identify as either straight, bisexual, or gay, who are ages 18-35 and are taking PrEP show original
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 90 day
Screening: ~3 weeks
Treatment: Varies
Reporting: 90 day
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 90 day.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether DOT mobile app will improve 1 primary outcome and 4 secondary outcomes in patients with Hiv. Measurement will happen over the course of 90 days.

PrEP adherence
90 DAYS
Wilson 3-item PrEP adherence self-report
90 DAYS
PrEP adherence self efficacy
90 DAYS
Johnson 12-item Adherence Self-Efficacy Scale (ASES)
90 DAYS
Intention to follow PrEP treatment guidelines
90 DAYS
5 item Intention to follow PrEP treatment guidelines developed by Weitzman & Kogelman
90 DAYS
Stress Burden
90 DAYS
10-item Perceived Stress Scale (Cohen et al., 1983)
90 DAYS
PrEP knowledge
90 DAY
6-item PrEP knowledge Tool, developed by Weitzman and Kogelman, to assess participants' knowledge of PrEP through questions about medication purpose, side effects, concomitant condom use, HIV testing
90 DAY

Who is running the study

Principal Investigator
P. W.
Patricia Weitzman, Senior Scientist
Environment and Health Group, Inc.

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can hiv be cured?

AIDS can be cured with a high success rate. The risk of death after being diagnosed with AIDS is reduced by over 90%. The survival rate is greater in women than in men and increases as time from diagnosis increases. Most people develop symptoms more than five years after being diagnosed with AIDS. The first treatment effective in curing HIV is highly active anti-retroviral therapy combined with highly active antiretroviral therapy. There is still significant public-health benefit from being diagnosed with HIV.

Anonymous Patient Answer

What causes hiv?

The risk of developing HIV infection increases significantly with age. There is no strong evidence to suggest that certain races are more prone to risk of HIV or that social or behavioural factors play a large part. HIV is related to the risk of acquiring hepatitis C.

Anonymous Patient Answer

What are common treatments for hiv?

Because of the heterogeneity of this condition, the treatment for HIV-infected people is individualistic. The mainstay of treatment is antiretroviral therapy, with or without other supportive therapy in more serious cases. More recent data have shown that antiretroviral therapy can be highly efficacious for a range of illnesses and in this case is also necessary to avert progression of HIV infection.\n

Anonymous Patient Answer

How many people get hiv a year in the United States?

The number of new HIV infections that occur in the United States was estimated at approximately 25,000 per year in this population based analysis. The current trajectory of HIV incidence could possibly decrease by about a third by 2030 if current trends continue after 2030.

Anonymous Patient Answer

What are the signs of hiv?

Not everyone develops HIV, however most people who test positive will acquire HIV over the course of their lifetimes. Sexual activity is the major risk factor that leads to HIV and AIDS. HIV is passed from a blood contaminated needle when used intravenously. HIV is passed through non-blood transmission via sexual contact. Symptoms of HIV include: swollen lymph nodes, persistent fever, rash, weight loss, sore throat and night sweats. In children and adolescents a high degree of parental anxiety may be a symptom. In pregnancy a woman may have more frequent vaginal and cervical bleeding than usual. If a pregnant woman gets HIV the woman can pass the virus to her unborn baby but this is normally not known before the pregnancy is halfway through.

Anonymous Patient Answer

What is hiv?

HIV is a serious and potentially life-threatening health issue. HIV, by cause, affects all racial and ethnic groups, and is generally transmitted horizontally through heterosexual activity. It is an infectious disease that infects humans with symptoms that vary between individuals, as well as causes the body to become incapable of preventing itself from infection.\n

Anonymous Patient Answer

Has dot mobile app proven to be more effective than a placebo?

Results from a recent paper demonstrates that mobile messaging is a highly effective mode of behaviour change with improved short and long term outcomes compared to a control group.

Anonymous Patient Answer

What is the average age someone gets hiv?

The average age of getting hiv is 24.8 and that is for boys and girls alike. The peak number of new cases is in the early 1990s, after which incidence is in decline. The main factor that influences incidence is sexual activity that is at its peak between 16 and 30, and also pregnancy and menopause that are at their lowest in adulthood\n\nThe first case of HIV in a male athlete was reported by French gyroscopist Pierre Tinel. He reported on a 15-year-old Greek boy who died on May 4, 1967 of Kaposi Sarcoma, "a skin disease caused by opportunistic infection by the human immunodeficiency virus" (HIV).

Anonymous Patient Answer

Does hiv run in families?

Recent findings provides some support for familial clustering of both HIV and AIDS. However, no family-based analysis of the time to onset (median age of diagnosis of family members ranged between 1.4 and 2.5 yr in this study) provides any definitive evidence of familial clustering.

Anonymous Patient Answer

What are the latest developments in dot mobile app for therapeutic use?

While the first version was for the treatment of diabetes, the second version also includes cancer therapy. The third version can be considered for immunization as well.

Anonymous Patient Answer

What is the primary cause of hiv?

In this group of young, predominantly Black men, the overwhelming majority of which were drug users, the only identified risk factor for infection with any form of this retrovirus was unsafe sexual activity. These data call to urgent attention the need for adequate and appropriate HIV-1 prevention education to reduce the risk for HIV-1 infection among drug users. Because they live in communities of young, predominantly African-Americans, the potential for the spread of HIV to a larger population cannot be ignored for this population. For this group of individuals, condom use is paramount in reducing the risk for human immunodeficiency virus infection by 95%, or more, as it had been proven in many of the studies that had been conducted to date.

Anonymous Patient Answer

What is the latest research for hiv?

In a recent study, findings are a bit disappointing. The latest research confirms previous results, that the viral load is most tightly controlled when using highly active antiretroviral treatment (HAART). However, the effects of HAART have become weaker and weaker over the last 5 years on patients’ health. HAART was once very effective in suppressing the amount of virus in people’s blood. This is because HAART is blocking the virus’ entry into the body. But now more and more of the viral strains that have escaped the antiretroviral drugs are becoming resistant to those drugs. But there are still drugs that can’t reach that level to eradicate the virus, which means that there has to be an alternative medicine.

Anonymous Patient Answer
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