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Opioid Analgesic

Fentanyl for Tonsillitis

Phase < 1
Waitlist Available
Led By Michael Montana, MD PhD
Research Sponsored by Washington University School of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 48 hours post surgery
Awards & highlights

Study Summary

This trial compared the effects of two different pain medications on post-surgery pain relief.

Eligible Conditions
  • Tonsillitis
  • Obstructive Sleep Apnea

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 48 hours post surgery
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 48 hours post surgery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Amount of rescue opioid medications administered - fentanyl group
Amount of rescue opioid medications administered - hydromorphone group
Evaluation of participant's pain - fentanyl group
+1 more
Secondary outcome measures
ASA physical status classification score from preoperative assessment - fentanyl group
ASA physical status classification score from preoperative assessment - hydromorphone group
Adverse events - fentanyl group
+11 more

Trial Design

2Treatment groups
Active Control
Group I: FentanylActive Control1 Intervention
Group II: HydromorphoneActive Control1 Intervention

Find a Location

Who is running the clinical trial?

Washington University School of MedicineLead Sponsor
1,933 Previous Clinical Trials
2,299,536 Total Patients Enrolled
1 Trials studying Tonsillitis
47 Patients Enrolled for Tonsillitis
Michael Montana, MD PhDPrincipal InvestigatorWashington University School of Medicine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How is Hydromorphone typically employed to ameliorate symptoms?

"Hydromorphone is often employed to treat anesthetic and nerve-related pain, as well as general anesthesia. Additionally, it has been used successfully to mitigate various other chronic pains."

Answered by AI

What eligibility criteria must potential participants meet in order to join this research project?

"Those with tonsillitis aged between 2 and 15 are eligible to partake in this medical experiment, which is recruiting a maximum of 300 individuals."

Answered by AI

Are new participants still being welcomed into this trial?

"Affirmative. The information on clinicaltrials.gov verifies that recruitment for this research is presently taking place, having first been posted in February 2020 and last edited in March of 2022. Altogether, 300 individuals from a single site are needed to participate in the trial."

Answered by AI

What is the maximum capacity of enrollees in this clinical investigation?

"Affirmative. Clinicaltrials.gov provides confirmation that this research study, initially posted on February 26th 2020, is currently recruiting patients. An estimated 300 participants will be recruited from 1 medical facility."

Answered by AI

Are adults aged 25 and above admissible for this research program?

"This clinical trial requires that participants are aged between 2 and 15 years old."

Answered by AI

Have any other investigative reports explored the impacts of Hydromorphone?

"Currently, 12 Phase 3 clinical trials for hydromorphone are active. Boston is the primary city with 54 of these experiments running while many other locations across America also host studies related to this medication."

Answered by AI

What is the purpose of this clinical experiment?

"The primary goal of this medical experiment, to be evaluated during the 48 hour period following surgery, is to assess pain levels in patients on fentanyl. Secondary evaluations consist of optional blood sample collection for hydromorphone and fentanyl concentrations as per mass spectroscopy analysis. Additionally, participants are also subjected to a rating system from ASA I-VI which evaluates their physical status prior to the operation."

Answered by AI
~37 spots leftby Apr 2025