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Behavior Therapy for Tourette Syndrome

Q: Does this experiment include seniors as participants?

The primary enrollment criteria for this trial includes individuals between 8 years of age and 17 years old.

Q: How many individuals have enrolled in this clinical exploration?

Affirmative. According to the clinicaltrials.gov listing, this experiment is actively looking for volunteers and began on December 15th 2022; it was most recently updated November 8th 2022. Currently, 10 people are needed from one site for participation.

Q: Who is the ideal participant for this research protocol?

This experiment is searching for around 10 individuals with <a href="https://www.withpower.com/clinical-trials/tourette-syndrome">tourette syndrome</a> who are between 8 and 17 years old.

Q: Are there current openings for this research project?

According to data hosted on clinicaltrials.gov, this trial is currently seeking participants and was initially posted on December 15th 2022 with the most recent update happening November 8th 2022.

Q: Can you tell me what prior experiments have been conducted on Behavior Therapy?

At present, 9 trials dedicated to Behavior Therapy research are currently underway with 2 having entered their final Phase 3. These studies are spread across 23 different locations in the United States; a major concentration of them is based out of Baltimore, <a href="https://www.withpower.com/clinical-trials/maryland">Maryland</a>.

Q: What psychological conditions are commonly treated with Behavior Therapy?

Behavior Therapy is commonly prescribed if traditional medical treatments fail to produce the desired outcome. It can additionally be utilized for various other diseases, including tuberculosis and extrapulmonary pulmonary TB which haven't responded to conventional therapy.

Phase < 1

Waitlist Available

Led By Joseph McGuire, PhD

Research Sponsored by Johns Hopkins University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up pre-treatment (baseline) and 1 week post-treatment

Awards & highlights

Study Summary

This trial is testing whether adding the drug d-cycloserine to behavior therapy can help reduce tic severity in people with Tourette's Disorder.

Eligible Conditions

Tourette Syndrome

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ pre-treatment (baseline) and 1 week post-treatment

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~pre-treatment (baseline) and 1 week post-treatment

This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-treatment (baseline) and 1 week post-treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Hopkins Motor/Vocal Tic Scale (HM/VTS) score

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Behavior Therapy + DCSExperimental Treatment2 Interventions

Youth with TD will receive four, 2-hour long sessions of evidence-based behavior therapy delivered in an intensive format. Participants will arrive an hour early for each session to take the d-cycloserine pill prior to starting each session of behavior therapy. Participants, therapists, and outcome assessors will be masked to pill condition.

Group II: Behavior Therapy + PlaceboActive Control2 Interventions

Youth with TD will receive four, 2-hour long sessions of evidence-based behavior therapy delivered in an intensive format. Participants will arrive an hour early for each session to take the placebo pill prior to starting each session of behavior therapy. Participants, therapists, and outcome assessors will be masked to pill condition.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

d-cycloserine

2018

Completed Phase 4

~630

Behavior Therapy

2016

Completed Phase 4

~1470

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor

2,256 Previous Clinical Trials

14,820,071 Total Patients Enrolled

7 Trials studying Tourette Syndrome

185 Patients Enrolled for Tourette Syndrome

Joseph McGuire, PhDPrincipal InvestigatorJohns Hopkins University

1 Previous Clinical Trials

40 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this experiment include seniors as participants?

"The primary enrollment criteria for this trial includes individuals between 8 years of age and 17 years old."

Answered by AI

How many individuals have enrolled in this clinical exploration?

"Affirmative. According to the clinicaltrials.gov listing, this experiment is actively looking for volunteers and began on December 15th 2022; it was most recently updated November 8th 2022. Currently, 10 people are needed from one site for participation."

Answered by AI

Who is the ideal participant for this research protocol?

"This experiment is searching for around 10 individuals with tourette syndrome who are between 8 and 17 years old."

Answered by AI

Are there current openings for this research project?

"According to data hosted on clinicaltrials.gov, this trial is currently seeking participants and was initially posted on December 15th 2022 with the most recent update happening November 8th 2022."

Answered by AI

Can you tell me what prior experiments have been conducted on Behavior Therapy?

"At present, 9 trials dedicated to Behavior Therapy research are currently underway with 2 having entered their final Phase 3. These studies are spread across 23 different locations in the United States; a major concentration of them is based out of Baltimore, Maryland."

Answered by AI

What psychological conditions are commonly treated with Behavior Therapy?

"Behavior Therapy is commonly prescribed if traditional medical treatments fail to produce the desired outcome. It can additionally be utilized for various other diseases, including tuberculosis and extrapulmonary pulmonary TB which haven't responded to conventional therapy."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

D-cycloserine Augmented Treatment for Youth With Tic Disorders

2023. "D-cycloserine Augmented Treatment for Youth With Tic Disorders". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04357951.