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cPMD rTMS + Training for Stroke

Phase < 1
Waitlist Available
Led By Ela Plow, PhD
Research Sponsored by The Cleveland Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline
Awards & highlights

Study Summary

This trialwill create new therapies to help stroke survivors with severe upper limb disabilities.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, on average 7 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, on average 7 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Inter-hemispheric Inhibition (IHI)
Change in Upper Extremity Fugyl-Meyer Score (UEFM)
Secondary outcome measures
Change Resting State Functional Magnetic Resonance Imaging(rsfMRI)
Change in Bimanual Grip Force Modulation Task
Change in SULCS
+4 more

Trial Design

2Treatment groups
Active Control
Group I: cPMD rTMS + TrainingActive Control1 Intervention
New Approach
Group II: iM1 rTMS + TrainingActive Control1 Intervention
Conventional Approach

Find a Location

Who is running the clinical trial?

American Heart AssociationOTHER
319 Previous Clinical Trials
4,932,399 Total Patients Enrolled
38 Trials studying Stroke
3,924,050 Patients Enrolled for Stroke
The Cleveland ClinicLead Sponsor
1,019 Previous Clinical Trials
1,365,052 Total Patients Enrolled
14 Trials studying Stroke
1,712 Patients Enrolled for Stroke
Ela Plow, PhDPrincipal InvestigatorLerner Research Institute; Cleveland Clinic Foundation
3 Previous Clinical Trials
109 Total Patients Enrolled
2 Trials studying Stroke
55 Patients Enrolled for Stroke

Media Library

cPMD rTMS + Training Clinical Trial Eligibility Overview. Trial Name: NCT03868410 — Phase < 1
Stroke Research Study Groups: cPMD rTMS + Training, iM1 rTMS + Training
Stroke Clinical Trial 2023: cPMD rTMS + Training Highlights & Side Effects. Trial Name: NCT03868410 — Phase < 1
cPMD rTMS + Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT03868410 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are being welcomed into this clinical experiment?

"Correct. Clinicaltrials.gov confirms that this research project, which was first posted on April 1st 2019, is actively accepting applications from participants. 24 individuals are required to be enrolled from a single medical centre."

Answered by AI

Are there any opportunities for me to participate in this clinical investigation?

"In order to be accepted into this research trial, candidates need to have had a stroke and must fall within the 18-90 year old age range. Currently, 24 participants are being recruited."

Answered by AI

What concrete outcomes is this study attempting to discern?

"The primary endpoint that will be examined over the duration of this study (on average 7 weeks) is a change in Upper Extremity Fugyl-Meyer Score. Secondary objectives include changes to diffusion tensor imaging, resting state functional magnetic resonance imaging, and reaching response time. These metrics help quantify neurophysiological interactions between contralesional and weak ipsilesional regions as well as global connectivity across multiple areas by tracking water magnitudes and directions through probabilistic tractography while also measuring white matter integrity with fractional anisotropy."

Answered by AI

Does this clinical trial accept participants aged under 25?

"This trial is open to individuals aged between 18 and 90. For those outside of this age range, 37 studies are available for minors while 1006 trials target the elderly population."

Answered by AI

Are there any opportunities for enrollees in the current clinical experiment?

"Affirmative. The clinical trial database hosted on clinicaltrials.gov verifies that this medical experiment is currently accepting enrolments and was first advertised to the public on April 1st 2019, with its most recent update occurring November 15th 2022. It's expected that 24 persons will be recruited at a single medical location for study involvement."

Answered by AI
Recent research and studies
~4 spots leftby Mar 2025