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Stellate Ganglion Block for Post-Traumatic Stress Disorder

Phase < 1
Waitlist Available
Led By Alan Peterson, PhD, ABPP
Research Sponsored by The University of Texas Health Science Center at San Antonio
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 1 month and 3 months
Awards & highlights

Study Summary

This trial is testing a new treatment for PTSD that combines exposure therapy with a stellate ganglion block injection.

Eligible Conditions
  • Post-Traumatic Stress Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 1 month and 3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1 month and 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in CAPS-5 (Clinician-Administered PTSD Scale)
Change in PCL-5 (Posttraumatic Stress Disorder Checklist)
Secondary outcome measures
Change in Brief Inventory of Psychosocial Functioning
Change in GAD-7 (General Anxiety Disorder Screener)
Change in PHQ-9 (Patient Health Questionnaire-9)
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Stellate Ganglion BlockExperimental Treatment1 Intervention
One time administration of a stellate ganglion block
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ropivacaine
FDA approved

Find a Location

Who is running the clinical trial?

The University of Texas Health Science Center at San AntonioLead Sponsor
452 Previous Clinical Trials
91,398 Total Patients Enrolled
United States Department of DefenseFED
864 Previous Clinical Trials
327,587 Total Patients Enrolled
Alan Peterson, PhD, ABPPPrincipal InvestigatorUniversity of Texas Health San Antonio Texas at San Antonio
2 Previous Clinical Trials
64 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Journal of Pain ResearchJournal
Ganglion Blocks as a Treatment of Pain: Current Perspectives
Gunduz, Osman Hakan, and Ozge Kenis Coskun. 2017. “Ganglion Blocks as a Treatment of Pain: Current Perspectives”. Journal of Pain Research. Informa UK Limited. doi:10.2147/jpr.s134775.
Military MedicineJournal
Stellate Ganglion Block Used to Treat Symptoms Associated with Combat-related Post-traumatic Stress Disorder: A Case Series of 166 Patients
Mulvaney, Sean W., James H. Lynch, Matthew J. Hickey, Tabassum Rahman-Rawlins, Matthew Schroeder, Shawn Kane, and Eugene Lipov. 2014. “Stellate Ganglion Block Used to Treat Symptoms Associated with Combat-related Post-traumatic Stress Disorder: A Case Series of 166 Patients”. Military Medicine. Oxford University Press (OUP). doi:10.7205/milmed-d-14-00151.
Annals of Clinical PsychiatryJournal
Cervical Sympathetic Blockade in a Patient with Post-traumatic Stress Disorder: A Case Report
Lipov, Eugene G., Jay R. Joshi, Sergei Lipov, Sarah E. Sanders, and Michelle K. Siroko. 2008. “Cervical Sympathetic Blockade in a Patient with Post-traumatic Stress Disorder: A Case Report”. Annals of Clinical Psychiatry. Portico. doi:10.1080/10401230802435518.
Military MedicineJournal
Effect of Stellate Ganglion Block on Specific Symptom Clusters for Treatment of Post-traumatic Stress Disorder
Lynch, James H., Sean W. Mulvaney, Eugene H. Kim, Jason B. de Leeuw, Matthew J. Schroeder, and Shawn F. Kane. 2016. “Effect of Stellate Ganglion Block on Specific Symptom Clusters for Treatment of Post-traumatic Stress Disorder”. Military Medicine. Oxford University Press (OUP). doi:10.7205/milmed-d-15-00518.
~3 spots leftby Apr 2025
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