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Losartan for Preeclampsia (LIVE-PE Trial)
LIVE-PE Trial Summary
This trial will help us to understand how losartan may improve vascular function in women with a history of preeclampsia and give us insight into the mechanisms behind the increased risk of cardiovascular disease in these women.
LIVE-PE Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowLIVE-PE Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2014 Phase 3 trial • 608 Patients • NCT00429364LIVE-PE Trial Design
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Who is running the clinical trial?
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- You have had diabetes during pregnancy in the past.I am taking medication to lower my cholesterol.You had high blood pressure before becoming pregnant.You are allergic to materials used during the experiment, like latex.I have or might have a liver, metabolic disease, or kidney disease with reduced function.I am currently taking medication for high blood pressure.I am a woman over 18 who had preeclampsia in my last pregnancy within the last 2 years.You are allergic to the study drugs.You currently smoke cigarettes or use tobacco products.I have a skin condition.Your body mass index (BMI) is too low, which means you might not have enough body weight to participate.
- Group 1: Losartan
- Group 2: Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the maximum enrollment capacity of this trial?
"Affirmative, the information available from clinicaltrials.gov suggests that this research is actively enrolling volunteers. This project was first posted on November 22nd 2020 and has been recently updated on May 16th 2022. It requires 20 participants to be recruited at one location."
Would I be eligible to participate in this experimental research?
"This medical study is recruiting 20 post-partum women aged 18 to 50 that have been diagnosed with preeclampsia. Furthermore, they must be utilizing an appropriate form of birth control and not plan to become pregnant in the next 6 months as per American College of Obstetricians and Gynecologists criteria for preeclampsia (information self reported by participants)."
Are recruitment efforts underway for this trial?
"According to clinicaltrials.gov, this medical trial is presently recruiting patients for enrollment. It was initially posted on November 22nd 2020 and the last iteration of modifications took place on May 16th 2022."
Has Losartan Potassium been trialed in other research premises?
"Presently, there are 30 investigations into the efficacy of Losartan Potassium with 2 trials in their final stage. While many of these studies take place at San Francisco medical centres, overall 533 locations across the country are running clinical trials involving this medication."
Does this study encompass participants aged 20 or older?
"This medical trial is seeking individuals between the ages of 18 to 50 who meet its inclusion criteria. Separately, 13 research studies are open for people under eighteen and 73 investigations have been launched for those over 65 years old."
How is Losartan Potassium typically employed to treat a medical condition?
"The common drug therapy for diabetic nephropathy is Losartan Potassium, which can also help mitigate left ventricular hypertrophy, proteinuria, and hypertensive disease."
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