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Bupivacaine Injection for Postoperative Pain

Phase < 1
Waitlist Available
Led By Karen Wang
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 7 days post-op
Awards & highlights

Study Summary

This trial is testing whether a short-acting non-opioid anesthetic can improve post-operative pain for patients undergoing minimally invasive hysterectomy.

Eligible Conditions
  • Postoperative Pain
  • Opioid Use Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 days post-op
This trial's timeline: 3 weeks for screening, Varies for treatment, and 7 days post-op for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Difference in post-operative opioid usage with the use of uterosacral ligament bupivacaine injection
Secondary outcome measures
Difference in Visual analog scores (VAS) scores following uterosacral ligament bupivicaine injection
Time to first bowel movement following uterosacral ligament bupivicaine injection

Trial Design

3Treatment groups
Active Control
Placebo Group
Group I: Bupivacaine InjectionActive Control1 Intervention
Bupivacaine will be injected into the uterosacral ligaments prior to colpotomy
Group II: Normal Saline InjectionPlacebo Group1 Intervention
Normal saline will be injected into the uterosacral ligaments prior to colpotomy
Group III: No injectionPlacebo Group1 Intervention
No injection will be performed

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,260 Previous Clinical Trials
14,820,600 Total Patients Enrolled
5 Trials studying Postoperative Pain
177 Patients Enrolled for Postoperative Pain
Karen WangPrincipal InvestigatorJohns Hopkins University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Intra-operative Uterosacral Ligament Bupivacaine Injection During Minimally Invasive Hysterectomy
2021. "Intra-operative Uterosacral Ligament Bupivacaine Injection During Minimally Invasive Hysterectomy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04157075.
~44 spots leftby Apr 2025
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