Furosemide for Bladder Preparation in Pelvic Ultrasounds
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether furosemide, a medication that helps the body eliminate excess salt and water, can make the bladder fill faster than using IV fluids alone. This could enable quicker and more effective pelvic ultrasounds. The trial includes two groups: one receiving only IV fluids and the other receiving IV fluids plus furosemide. Girls aged 8-18 undergoing a pelvic ultrasound in the emergency department (to check for twisted ovaries) may qualify if they do not have certain medical conditions, such as kidney issues or previous surgeries in the area. As an Early Phase 1 trial, this research aims to understand how furosemide works in people, offering participants a chance to contribute to medical advancements.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you have used diuretics in the past year, you may not be eligible to participate.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research shows that furosemide, also known as Lasix, is generally safe for use. Studies have found it can be administered without major side effects in various situations. However, monitoring kidney function, especially in children, is crucial to ensure the body handles the drug well. Overall, furosemide is well-tolerated, making it a viable option for aiding bladder filling during pelvic ultrasounds.12345
Why do researchers think this study treatment might be promising?
Researchers are excited about using furosemide for bladder preparation in pelvic ultrasounds because it offers a unique approach compared to current methods. Typically, bladder preparation involves patients drinking large amounts of water, which can be uncomfortable and time-consuming. Furosemide, a diuretic, works differently by stimulating the kidneys to produce urine more quickly, which could lead to faster and potentially more comfortable bladder filling. This new method could streamline the ultrasound process and improve patient comfort, making it a promising alternative to traditional water-loading techniques.
What evidence suggests that furosemide might be an effective treatment for bladder preparation in pelvic ultrasounds?
Studies have shown that furosemide helps the bladder fill faster than IV fluids alone, particularly in young women needing a pelvic ultrasound. In this trial, participants will receive either furosemide or IV fluids alone. Furosemide can make the process quicker and more efficient by speeding up bladder filling. Although the results are promising, further research is needed to confirm these early findings.13567
Who Is on the Research Team?
Candice Jersey, D.O.
Principal Investigator
Connecticut Children's Medical Center
Are You a Good Fit for This Trial?
This trial is for girls aged 8-18 who need a pelvic ultrasound in the emergency department to check for ovarian torsion. They must be able to consent or have a guardian who can, and not be critically ill, pregnant, on diuretics recently, or have kidney/genitourinary issues.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either IV fluids alone or IV fluids with furosemide to expedite bladder filling
Follow-up
Participants are monitored for adverse events and bladder volume correlation after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Furosemide
Find a Clinic Near You
Who Is Running the Clinical Trial?
Connecticut Children's Medical Center
Lead Sponsor