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Furosemide for Bladder Preparation in Pelvic Ultrasounds

Q: How many participants are involved in this research project?

Affirmative. Clinicaltrials.gov verifies that this medical trial, which was initially published on the 29th of May 2021, is currently recruiting participants. 100 patients will be accepted at one location for this study.

Q: What medical conditions can Furosemide be utilized to alleviate?

Furosemide is regularly prescribed for <a href="https://www.withpower.com/clinical-trials/congestive-heart-failure">congestive heart failure</a> and can prove beneficial in the management of conditions like edema, pulmonary edema, and <a href="https://www.withpower.com/clinical-trials/hypertension">hypertension</a>.

Q: Are there any open slots in this clinical research endeavor?

Affirmative. Clinicaltrials.gov corroborates that this clinical trial, which was first posted on May 29th 2021, is actively in search of participants. Approximately 100 people will be needed to join from a single medical centre.

Q: What other studies have explored the usage of Furosemide?

At present, 15 Furosemide-focused clinical trials are underway. Of these studies, 6 have progressed to Phase 3 and can be found in 43 separate medical centres across Houston, <a href="https://www.withpower.com/clinical-trials/texas">Texas</a>.

Q: Does this research endeavor include participants aged 80 or above?

Based on the trial's eligibility requirements, applicants must be aged 8 and above yet below 18 years old.

Q: Would I be eligible to volunteer for this medical research?

One hundred individuals with ovarian torsion aged 8 to 18 years are being enrolled in this trial. The primary requirement for candidacy is that the patient must be female and have undergone a trans-abdominal pelvic ultrasound at CCMC Emergency Department (ED).

Phase < 1

Recruiting

Led By Candice Jersey, D.O.

Research Sponsored by Connecticut Children's Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from time of intervention until final disposition, about 6 hours

Awards & highlights

Study Summary

This trial will test whether furosemide causes the bladder to fill faster, allowing for a quicker ultrasound exam.

Who is the study for?

This trial is for girls aged 8-18 who need a pelvic ultrasound in the emergency department to check for ovarian torsion. They must be able to consent or have a guardian who can, and not be critically ill, pregnant, on diuretics recently, or have kidney/genitourinary issues.Check my eligibility

What is being tested?

The study is testing if Furosemide helps fill the bladder quicker than just IV fluids for better ultrasound imaging. It's comparing these two methods in young females awaiting pelvic ultrasounds.See study design

What are the potential side effects?

Furosemide may cause increased urination, dehydration risks, electrolyte imbalances (like low potassium), and possible allergic reactions if there's a sulfonamide medication allergy.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from time of intervention until final disposition, about 6 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from time of intervention until final disposition, about 6 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and from time of intervention until final disposition, about 6 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

The time from initiation of the intervention to the time that the bladder reaches large, ovoid shape on POCUS exam

Secondary outcome measures

Number and nature of all reports of adverse events related to furosemide administration

The correlation between bladder volume as calculated on POCUS exam of a large, ovoid bladder and bladder volume as reported by bladder scanner

The time from initiation of intervention to the time of admission or discharge order placement

+1 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: FurosemideExperimental Treatment1 Intervention

Participants will receive a 20mL/kg (max 1000mL) IV fluid bolus and a 0.1mg/kg (max 5mg) furosemide dose

Group II: IV fluidsPlacebo Group1 Intervention

Participants will receive a 20mL/kg (max 1000mL) IV fluid bolus and an IV fluid flush

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Furosemide

FDA approved

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Connecticut Children's Medical CenterLead Sponsor

71 Previous Clinical Trials

31,414 Total Patients Enrolled

Candice Jersey, D.O.Principal InvestigatorConnecticut Children's Medical Center

Media Library

Furosemide Clinical Trial Eligibility Overview. Trial Name: NCT05098366 — Phase < 1

Ovarian Torsion Research Study Groups: IV fluids, Furosemide

Ovarian Torsion Clinical Trial 2023: Furosemide Highlights & Side Effects. Trial Name: NCT05098366 — Phase < 1

Furosemide 2023 Treatment Timeline for Medical Study. Trial Name: NCT05098366 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are involved in this research project?

"Affirmative. Clinicaltrials.gov verifies that this medical trial, which was initially published on the 29th of May 2021, is currently recruiting participants. 100 patients will be accepted at one location for this study."

Answered by AI

What medical conditions can Furosemide be utilized to alleviate?

"Furosemide is regularly prescribed for congestive heart failure and can prove beneficial in the management of conditions like edema, pulmonary edema, and hypertension."

Answered by AI

Are there any open slots in this clinical research endeavor?

"Affirmative. Clinicaltrials.gov corroborates that this clinical trial, which was first posted on May 29th 2021, is actively in search of participants. Approximately 100 people will be needed to join from a single medical centre."

Answered by AI

What other studies have explored the usage of Furosemide?

"At present, 15 Furosemide-focused clinical trials are underway. Of these studies, 6 have progressed to Phase 3 and can be found in 43 separate medical centres across Houston, Texas."

Answered by AI

Does this research endeavor include participants aged 80 or above?

"Based on the trial's eligibility requirements, applicants must be aged 8 and above yet below 18 years old."

Answered by AI

Would I be eligible to volunteer for this medical research?

"One hundred individuals with ovarian torsion aged 8 to 18 years are being enrolled in this trial. The primary requirement for candidacy is that the patient must be female and have undergone a trans-abdominal pelvic ultrasound at CCMC Emergency Department (ED)."

Answered by AI

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