NV701 vs Pilocarpine Eye Drops for Vision Issues
Recruiting at 1 trial location
SD
Overseen ByStudy Director
Age: 18 - 65
Sex: Any
Trial Phase: Phase < 1
Sponsor: Novus Vision LLC
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Trial Summary
What is the purpose of this trial?
Randomized contralateral eye study to evaluate the effect of one-time dosing of NV701 versus commercially available 1.25% pilocarpine solution on pupil size.
Eligibility Criteria
This trial is for individuals with presbyopia, a condition where the eyes lose the ability to focus on close objects, leading to constricted pupils. Participants should not have any other significant eye conditions that could interfere with the study.Inclusion Criteria
My pupils change size significantly after using pilocarpine eye drops.
Able to understand and willing to sign the informed consent for the study
Resting mesopic pupil diameter of >4 mm in both eyes
See 3 more
Exclusion Criteria
I have had eyelid or droopy eyelid surgery.
Known allergy to any of the study products or medications
I have a specific eye condition diagnosed by a doctor.
See 16 more
Timeline
Screening
Participants are screened for eligibility to participate in the trial
1-2 weeks
Treatment
One-time administration of NV701 or Vuity (1.25% pilocarpine) to evaluate effect on pupil size
1 day
1 visit (in-person)
Follow-up
Participants are monitored for changes in pupil size over 8 hours after treatment
8 hours
1 visit (in-person)
Treatment Details
Interventions
- NV701
Trial Overview The study is testing NV701 against Vuity (both are pilocarpine 1.25% eye drops) to see which one better controls pupil size in people with presbyopia. Each participant's eyes will receive different treatments for comparison.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: NV701Experimental Treatment1 Intervention
1 drop of NV701 (1.25% pilocarpine)
Group II: VuityActive Control1 Intervention
1 drop of Vuity (1.25% pilocarpine) in contralateral eye
Find a Clinic Near You
Who Is Running the Clinical Trial?
Novus Vision LLC
Lead Sponsor
Trials
1
Recruited
50+
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