MDMA for Social Behavior

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Chicago, Chicago, IL
Social Behavior+3 More
MDMA - Drug
Eligibility
18 - 65
All Sexes
What conditions do you have?
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Study Summary

To study the effects of MDMA, compared to a prototypical stimulant, on social motivation, social ability, and neural indices of social function in healthy volunteers

Eligible Conditions

  • Social Behavior
  • MDMA ('Ecstasy')
  • Motivation
  • Stimulant Use

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Social Behavior

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Time Frame: Baseline-72 hours after completion of the sessions

Hour 72
Profile of Mood States

Trial Safety

Safety Progress

1 of 3

Other trials for Social Behavior

Trial Design

3 Treatment Groups

Experimental: Placebo Then MDMA Then Methamphetamine
1 of 3
Experimental: MDMA Then Placebo Then Methampetamine
1 of 3
Experimental: Methampetamine Then Placebo Then MDMA
1 of 3
Experimental Treatment

36 Total Participants · 3 Treatment Groups

Primary Treatment: MDMA · Has Placebo Group · Phase < 1

Experimental: Placebo Then MDMA Then MethamphetamineExperimental Group · 3 Interventions: MDMA, Methamphetamine, placebo oral tablet · Intervention Types: Drug, Drug, Drug
Experimental: MDMA Then Placebo Then MethampetamineExperimental Group · 3 Interventions: MDMA, Methamphetamine, placebo oral tablet · Intervention Types: Drug, Drug, Drug
Experimental: Methampetamine Then Placebo Then MDMAExperimental Group · 3 Interventions: MDMA, Methamphetamine, placebo oral tablet · Intervention Types: Drug, Drug, Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MDMA
2017
Completed Phase 3
~490
Methamphetamine
2013
Completed Phase 1
~50
placebo oral tablet
2021
Completed Phase 2
~570

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: time frame: baseline-72 hours after completion of the sessions
Closest Location: University of Chicago · Chicago, IL
Photo of University of Chicago 1Photo of University of Chicago 2Photo of University of Chicago 3
2004First Recorded Clinical Trial
1 TrialsResearching Social Behavior
705 CompletedClinical Trials

Who is running the clinical trial?

University of ChicagoLead Sponsor
909 Previous Clinical Trials
726,861 Total Patients Enrolled
1 Trials studying Social Behavior
220 Patients Enrolled for Social Behavior

Eligibility Criteria

Age 18 - 65 · All Participants · 3 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.