← Back to Search

Ketone Supplement

Nutrition Ketogenic Supplement for Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency

Q: What would be the desired outcome of this research?

This trial seeks to gain insight into the effects of product intake on Diarrhea over a two hour period. Additionally, Blood Ketones, Blood Creatine Kinase and Blood Lactate levels will be monitored as secondary objectives.

Q: Is it currently feasible to join this experiment?

According to the clinicaltrials.gov portal, this research endeavour is in its recruitment phase with a start date of August 1st 2022 and last edit made on October 3rd 2022.

Q: What is the upper limit of participants for this clinical investigation?

Affirmative. According to the clinicaltrials.gov portal, this medical trial is currently recruiting patients with its inception date listed as August 1st 2022 and most recently updated on October 3rd 2022. The research team requires 5 individuals from one hospital site for participation in their study.

Phase < 1

Waitlist Available

Research Sponsored by Oregon Health and Science University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up peak 40 minute exercise

Awards & highlights

Study Summary

This trial will test if a ketone drink is safe and tolerable for people with disorders that prevent the body from burning fats properly, and if it will raise blood ketone levels as much as is seen in healthy people.

Eligible Conditions

Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
Carnitine Palmitoyltransferase Deficiency 2
Trifunctional Protein Deficiency
Acyl CoA Dehydrogenase Deficiency

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ peak 40 minute exercise

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~peak 40 minute exercise

This trial's timeline: 3 weeks for screening, Varies for treatment, and peak 40 minute exercise for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Abdominal discomfort

Adverse Events- causal relationship

Adverse Events- incidence

+7 more

Secondary outcome measures

Blood Creatine Kinase

Blood Glucose

Blood Ketones

+5 more

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Nutrition Ketogenic SupplementActive Control1 Intervention

The Ketone pre-exercise beverage is a nutritional supplement. The supplement will be provided by Nestle as powered sachets to mix in water. It contains a mix of D-beta-hydroxybutyrate salts, flavors and stevia.

Group II: Isocaloric Placebo SupplementPlacebo Group1 Intervention

The maltodextrin pre-exercise beverage is a nutritional supplement. The supplement will be provided by Nestle as powered sachets to mix in water. It contains an isocaloric amount of maltodextrin, flavors and stevia similar to the ketone beverage.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Oregon Health and Science UniversityLead Sponsor

973 Previous Clinical Trials

6,846,024 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What would be the desired outcome of this research?

"This trial seeks to gain insight into the effects of product intake on Diarrhea over a two hour period. Additionally, Blood Ketones, Blood Creatine Kinase and Blood Lactate levels will be monitored as secondary objectives."

Answered by AI

Is it currently feasible to join this experiment?

"According to the clinicaltrials.gov portal, this research endeavour is in its recruitment phase with a start date of August 1st 2022 and last edit made on October 3rd 2022."

Answered by AI

What is the upper limit of participants for this clinical investigation?

"Affirmative. According to the clinicaltrials.gov portal, this medical trial is currently recruiting patients with its inception date listed as August 1st 2022 and most recently updated on October 3rd 2022. The research team requires 5 individuals from one hospital site for participation in their study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Oral Ketones and Exercise Among Patients With Long-chain Fatty Acid Oxidation Disorders

Melanie B Gillingham 2022. "Oral Ketones and Exercise Among Patients With Long-chain Fatty Acid Oxidation Disorders". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05411835.